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Is α-Keratin a Coiled Coil?

Abstract

ALL recent work1–6 has confirmed that the structure of the synthetic polypeptide poly-γ-methyl-L-glutamate is based on the α-helix of Pauling and Corey7. This structure gives a strong 1.5-A. reflexion on the meridian, and both MacArthur8 and Perutz1 have shown that this reflexion also occurs in α-keratin. This suggests forcibly that the α-helix forms an important part of α-keratin.

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References

  1. Perutz, M. F., Nature, 167, 1053 (1951).

    Article  ADS  CAS  Google Scholar 

  2. Cochran, W., and Crick, F. H. C., Nature, 169, 234 (1952).

    Article  ADS  CAS  Google Scholar 

  3. Bamford, C. H., Brown, L., Elliott, A., Hanby, W. E., and Trotter, I. F., Nature, 169, 357 (1952).

    Article  ADS  CAS  Google Scholar 

  4. Yakel, H. L., Pauling, L., and Corey, R. B., Nature, 169, 920 (1952).

    Article  ADS  CAS  Google Scholar 

  5. Fraser, R. D. B., and Price, W. C., Nature, 170, 490 (1952).

    Article  ADS  CAS  Google Scholar 

  6. Cochran, W., Crick, F. H. C., and Vand, V., Acta Cryst., 5, 581 (1952).

    Article  CAS  Google Scholar 

  7. Pauling, L., and Corey, R. B., Proc. U.S. Nat. Acad. Sci., 37, 241 (1951).

    Article  ADS  CAS  Google Scholar 

  8. MacArthur, I., Nature, 152, 38 (1943).

    Article  ADS  CAS  Google Scholar 

  9. Bear, R. S., J. Amer. Chem. Soc., 65, 1784 (1943).

    Article  CAS  Google Scholar 

  10. Davies, M., Ann. Rep. Chem. Soc., 43, 1 (1946).

    Google Scholar 

  11. Crick, F. H. C., Acta Cryst., 5, 381 (1952).

    Article  CAS  Google Scholar 

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CRICK, F. Is α-Keratin a Coiled Coil?. Nature 170, 882–883 (1952). https://doi.org/10.1038/170882b0

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