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Phosphorylation on the Primitive Earth: Phosphorylation by way of Inorganic Phosphate as a Potential Prebiotic Process

Abstract

Conditions can be created in which inorganic phosphates act as phosphorylating agents. Such reactions may have occurred in prebiotic chemical processes.

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References

  1. Katchman, B. J., Phosphorus and its Compounds (edit. by Van Wazer, J. R.) (Interscience Publishers, New York, 1961).

    Google Scholar 

  2. Brown, D. M., Advances in Organic Chemistry, Methods and Results (edit. by Raphael, R. A., Taylor, E. C., and Wynberg, H.) (Interscience Publishers, New York, 1963).

    Google Scholar 

  3. Khorana, H. G., Some Recent Developments in the Chemistry of Phosphate Esters of Biological Interest (John Wiley and Sons, New York, 1961).

    Google Scholar 

  4. Cherbuliez, E., Colak-Antic, S., Prince, R., and Rabinowitz, J., Helv. Chim. Acta, 47, 1657 (1964).

    Google Scholar 

  5. Schofield, J. A., and Todd, A. R., J. Chem. Soc., 2316 (1961).

  6. Kirby, A. J., and Warren, S. G., The Organic Chemistry of Phosphorus (Elsevier, New York, 1967).

    Google Scholar 

  7. Steinman, G., Lemmon, R. M., and Calvin, M., Proc. US Nat. Acad. Sci., 52, 27 (1964).

    Article  ADS  CAS  Google Scholar 

  8. Waehneldt, T. V., and Fox, S. W., Biochim. Biophys. Acta, 134, 1 (1967).

    Article  CAS  Google Scholar 

  9. Ponnamperuma, C., and Mack, R., Science, 148, 1221 (1965).

    Article  ADS  CAS  Google Scholar 

  10. Skoda, J., and Moravek, J., Tetrahedron Lett., 4167 (1966).

  11. Moravek, J., and Skoda, J., Collection Czech. Chem. Commun., 32, 206 (1967).

    Article  CAS  Google Scholar 

  12. Karl-Kroupa, E., Anal. Chem., 28, 1091 (1956).

    Article  CAS  Google Scholar 

  13. Fuchs, R. J., and Czeck, F. W., Anal. Chem., 35, 769 (1963).

    Article  CAS  Google Scholar 

  14. Miller, S. L., and Parris, M., Nature, 204, 1248 (1964).

    Article  ADS  CAS  Google Scholar 

  15. Van Wazer, J. R., Phosphorus and its Compounds, chap. 10 (Interscience, New York, 1958).

    Google Scholar 

  16. Beck, A., and Orgel, L. E., Proc. US Nat. Acad. Sci., 54, 664 (1965).

    Article  ADS  CAS  Google Scholar 

  17. Harold, F. M., Bact. Rev., 30, 772 (1966).

    CAS  Google Scholar 

Download references

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RABINOWITZ, J., CHANG, S. & PONNAMPERUMA, C. Phosphorylation on the Primitive Earth: Phosphorylation by way of Inorganic Phosphate as a Potential Prebiotic Process. Nature 218, 442–443 (1968). https://doi.org/10.1038/218442a0

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