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Antigenic Expression of a Murine Lymphoma during Growth in vitro

Abstract

WHILE studying a Moloney virus (MV) induced lymphoma in culture, we were puzzled by the disappearance of the antibody-mediated cytotoxic sensitivity of the cells several days after explantation. After a longer time in culture, however, these cells regained sensitivity to the same sera with complement. The experiments have been repeated in better controlled conditions, and some of the results obtained are reported here.

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CIKES, M. Antigenic Expression of a Murine Lymphoma during Growth in vitro. Nature 225, 645–647 (1970). https://doi.org/10.1038/225645a0

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