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Stability of Cardiac Monoamine Oxidase Activity after Chemical Sympathectomy with 6-Hydroxydopamine

Nature volume 228, pages 175–176 (1970)Cite this article

Abstract

MONOAMINE oxidase (MAO) of sympathetically innervated organs has been classically considered to be involved in the regulation of intraneuronal catecholamine concentrations. This function of MAO implies that the enzyme is located within the presynaptic element of the adrenergic neuroeffector system. Recent studies, however, have indicated that MAO may be located extraneuronally1,2.

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Authors and Affiliations

  1. Department of Pharmacology, School of Medicine, University of Washington, Seattle, Washington, 98105

    M. C. LOWE & A. HORITA

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  1. M. C. LOWE
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  2. A. HORITA
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LOWE, M., HORITA, A. Stability of Cardiac Monoamine Oxidase Activity after Chemical Sympathectomy with 6-Hydroxydopamine. Nature 228, 175–176 (1970). https://doi.org/10.1038/228175a0

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