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Temperature-sensitive Mammalian Cell Line Blocked in Mitosis

Abstract

SEVERAL temperature-sensitive mammalian cell mutants in culture have been isolated1–10, including three defective in protein syntheses6, cytokinesis5 and the processing of ribosomal RNA10, respectively. I have now isolated a hamster cell mutant in which mitosis is blocked in metaphase.

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WANG, R. Temperature-sensitive Mammalian Cell Line Blocked in Mitosis. Nature 248, 76–78 (1974). https://doi.org/10.1038/248076a0

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  • DOI: https://doi.org/10.1038/248076a0

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