Abstract
IT is well established that physical exercise causes an increase in sympathetic activity, as shown by rises in the levels of plasma and urine catecholamines1. This increase in endogenous adrenergic activity can be used to study the effects of sympathetic stimulation. Such studies usually compare a control situation with one in which either α or β adrenergic receptor activity is blocked pharmacologically, thereby allowing study of both the blocked and unblocked receptors. Beta blocking drugs have been used in this way to study changes in carbohydrate metabolism2, free fatty acid metabolism3, and blood coagulation and fibrinolysis4 induced by exercise.
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IRVING, M., BRITTON, B., WOOD, W. et al. Effects of β adrenergic blockade on plasma catecholamines in exercise. Nature 248, 531–533 (1974). https://doi.org/10.1038/248531a0
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DOI: https://doi.org/10.1038/248531a0
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