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Cytological detection of mutagen–carcinogen exposure by sister chromatid exchange

Nature volume 258, pages 121–125 (1975)Cite this article

Abstract

A staining technique that detects sister chromatid exchanges (SCEs) has been used to examine the response of chromosomes in cultured Chinese hamster cells to a wide variety of mutagens–carcinogens. The test gives a very sensitive and rapid method for detecting chromosome mutagenicity of chemical agents and provides a powerful new method for detecting environmental mutagens.

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Authors and Affiliations

  1. MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh, EH4 2XU, UK

    P. Perry & H. J. Evans

Authors
  1. P. Perry
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  2. H. J. Evans
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Perry, P., Evans, H. Cytological detection of mutagen–carcinogen exposure by sister chromatid exchange. Nature 258, 121–125 (1975). https://doi.org/10.1038/258121a0

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