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Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane

Nature volume 269, pages 307–311 (1977)Cite this article

Abstract

Human HLA-A, B, C and Ia antigens were labelled by lactoperoxidase-catalysed iodination of the inner surface of lymphocyte plasma membrane and thus are transmembrane proteins. In contrast, membrane-bound human IgM and mouse IgM, IgD and Thy-1 antigen were not labelled on the inner membrane surface.

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Author notes

  1. Frank S. Walsh

    Present address: Laboratory of Biochemical Genetics, National Institutes of Health, Bethesda, MD, 20014, USA

Authors and Affiliations

  1. National Institute for Medical Research, Mill Hill, London, NW7, UK

    Frank S. Walsh & Michael J. Crumpton

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  1. Frank S. Walsh
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  2. Michael J. Crumpton
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Walsh, F., Crumpton, M. Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane. Nature 269, 307–311 (1977). https://doi.org/10.1038/269307a0

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