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Unusual response of DDT-resistant houseflies to carbinol analogues of DDT

Abstract

THE toxic action of DDT is thought to be caused by complex formation between the insecticide and nerve protein, a mechanism consistent with the well known phenomenon of negative correlation between insect mortality and temperature1. We present here evidence which indicates that some carbinols which are close analogues of DDT may have a different mode of action. These compounds elicit very different symptoms of poisoning, and none of the major mechanisms of resistance to DDT in the housefly confers significant resistance to these compounds.

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SAWICKI, R. Unusual response of DDT-resistant houseflies to carbinol analogues of DDT. Nature 275, 443–444 (1978). https://doi.org/10.1038/275443a0

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