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Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA

Nature volume 282, pages 471–477 (1979)Cite this article

Abstract

A synthetic fowl plague virus (FPV) haemagglutinin gene has been cloned in bacteria and the complete sequence of the RNA gene deduced. It is 1,742 nucleotides long and the mRNA codes for 563 amino acids in an uninterrupted sequence. The nature of some of the important domains in the haemagglutinin has been established, and their structure is discussed in relation to their function. Extensive amino acid sequence homologies exist between FPV and human influenza haemagglutinins.

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Authors and Affiliations

  1. Searle Research Laboratories, Lane End Road, High Wycombe, Bucks, UK

    A. G. Porter, C. Barber, N. H. Carey, R. A. Hallewell, G. Threlfall & J. S. Emtage

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  1. A. G. Porter
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  2. C. Barber
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  3. N. H. Carey
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  4. R. A. Hallewell
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  5. G. Threlfall
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  6. J. S. Emtage
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Porter, A., Barber, C., Carey, N. et al. Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA. Nature 282, 471–477 (1979). https://doi.org/10.1038/282471a0

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