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The structure of eight distinct cloned human leukocyte interferon cDNAs

Abstract

Eight classes of human leukocyte interferon (LeIFN) cDNA clones have been identified in a cDNA library prepared from a myeloblastoid cell line. The nucleotide sequences demonstrate that the multiple human LeIFN genes code for a family of homologous, yet distinct proteins. One of the cDNA clones may have been derived from the transcription of a LeIFN pseudogene.

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Goeddel, D., Leung, D., Dull, T. et al. The structure of eight distinct cloned human leukocyte interferon cDNAs. Nature 290, 20–26 (1981). https://doi.org/10.1038/290020a0

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