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Evolution of tumours and the impact of molecular oncology

Abstract

It is generally accepted that tumours arise through the accumulation of several changes affecting the control of cell growth. Recent advances in molecular biology have made it possible to define some of these changes in molecular terms and to trace the steps by which certain tumours evolve.

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Klein, G., Klein, E. Evolution of tumours and the impact of molecular oncology. Nature 315, 190–195 (1985). https://doi.org/10.1038/315190a0

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