Abstract
Subpopulations of RNA molecules that bind specifically to a variety of organic dyes have been isolated from a population of random sequence RNA molecules. Roughly one in 1010 random sequence RNA molecules folds in such a way as to create a specific binding site for small ligands.
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Ellington, A., Szostak, J. In vitro selection of RNA molecules that bind specific ligands. Nature 346, 818–822 (1990). https://doi.org/10.1038/346818a0
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DOI: https://doi.org/10.1038/346818a0
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