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Three-dimensional Structure of Thermolysin

Abstract

The electron density map of thermolysin indicates how the polypeptide chain is displaced throughout the overall shape of the molecule.

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References

  1. Titani, K., Hermodson, M. A., Ericsson, L. H., Walsh, K. A., and Neurath, H., Nature New Biology, 238, 35 (1972).

    Article  CAS  Google Scholar 

  2. Matthews, B. W., Colman, P. M., Jansonius, J. N., Titani, K., Walsh, K. A., and Neurath, H., Nature New Biology, 238, 41 (1972).

    Article  CAS  Google Scholar 

  3. Green, D. W., Ingram, V. M., and Perutz, M. F., Proc. Roy. Soc, A, 225, 287 (1954).

    CAS  Google Scholar 

  4. Hart, R. G., Acta Cryst., 14, 1188 (1961).

    Article  Google Scholar 

  5. Blake, C. C. F., Koenig, D. F., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Nature, 206, 757 (1965).

    Article  CAS  Google Scholar 

  6. Blow, D. M., and Crick, F. H. C., Acta Cryst., 12, 794 (1959).

    Article  CAS  Google Scholar 

  7. North, A. C. T., Acta Cryst., 18, 212 (1965).

    Article  CAS  Google Scholar 

  8. Matthews, B. W., Acta Cryst., 20, 82 (1966).

    Article  CAS  Google Scholar 

  9. Matthews, B. W., in Crystallographic Computing (edit. by Ahmed, F. R.), 146 (1970).

    Google Scholar 

  10. Latt, S. A., Holmquist, B., and Vallee, B. L., Biochem. Biophys. Res. Commun., 37, 333 (1969).

    Article  CAS  Google Scholar 

  11. Richards, F. M., J. Mol. Biol, 37, 225 (1968).

    Article  CAS  Google Scholar 

  12. Rudko, A. D., and Low, B. W., J. Appl. Cryst., 3, 545 (1970).

    Article  Google Scholar 

  13. Kendrew, J. C., Dickerson, R. E., Strandberg, B. E., Hart, R. G., Davies, D. R., Phillips, D. C., and Shore, V. C., Nature, 185, 422 (1960).

    Article  CAS  Google Scholar 

  14. Pauling, L., Corey, R. B., and Branson, H. R., Proc. US Nat. Acad. Sci., 37, 205 (1951).

    Article  CAS  Google Scholar 

  15. Drucker, H., and Yang, J. T., Fed. Proc., 28, Biochem. Abstr., 3306 (1969).

  16. Morihara, K., and Oka, T., Biochem. Biophys. Res. Commun., 30, 625 (1968).

    Article  CAS  Google Scholar 

  17. Blow, D. M., Biochem. J., 112, 261 (1969).

    Article  CAS  Google Scholar 

  18. Drenth, J., Jansonius, J. N., Koekoek, R., Swen, H. M., and Wolthers, B. G., Nature, 218, 929 (1968).

    Article  CAS  Google Scholar 

  19. Wright, C. S., Alden, R. A., and Kraut, J., Nature, 221, 235 (1969).

    Article  CAS  Google Scholar 

  20. Shotton, D. M., and Watson, H. C., Nature, 225, 811 (1970).

    Article  CAS  Google Scholar 

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MATTHEWS, B., JANSONIUS, J., COLMAN, P. et al. Three-dimensional Structure of Thermolysin. Nature New Biology 238, 37–41 (1972). https://doi.org/10.1038/newbio238037a0

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