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Rheumatoid arthritis

Microvascular clues to hemiplegia-induced asymmetric RA

Patients with rheumatoid arthritis who are hemiplegic, and also mice with denervated hindpaws and experimentally-induced arthritis, can develop unilateral arthritis. But is a specific branch of the nervous system involved in this asymmetry, or does a lack of innervation alter the microvasculature and promote vascular impermeability?

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Correspondence to Alisa E. Koch.

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A.E.K declares that she is a Senior Medical Fellow at Eli Lilly and Company. B.J.R. declares no competing interests.

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Rabquer, B., Koch, A. Microvascular clues to hemiplegia-induced asymmetric RA. Nat Rev Rheumatol 10, 701–702 (2014). https://doi.org/10.1038/nrrheum.2014.159

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