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Bone marrow transplantation as treatment for X-linked immunodeficiency with hyper-IgM

Abstract

We report a 10-year-old boy with a severe form of immunodeficiency with hyper-IgM who underwent successful bone marrow transplantation with his HLA-matched sister as donor. Busulfan (20 mg/kg) and cyclophosphamide (200 mg/kg) were used as conditioning. The post-transplant course was uneventful. He is alive 25 months later with full hematological and immunological reconstitution.

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Bordigoni, P., Auburtin, B., Carret, AS. et al. Bone marrow transplantation as treatment for X-linked immunodeficiency with hyper-IgM. Bone Marrow Transplant 22, 1111–1114 (1998). https://doi.org/10.1038/sj.bmt.1701497

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  • DOI: https://doi.org/10.1038/sj.bmt.1701497

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