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Ets target genes: past, present and future

Oncogene volume 19, pages 6533–6548 (2000)Cite this article

Abstract

Ets is a family of transcription factors present in species ranging from sponges to human. All family members contain an approximately 85 amino acid DNA binding domain, designated the Ets domain. Ets proteins bind to specific purine-rich DNA sequences with a core motif of GGAA/T, and transcriptionally regulate a number of viral and cellular genes. Thus, Ets proteins are an important family of transcription factors that control the expression of genes that are critical for several biological processes, including cellular proliferation, differentiation, development, transformation, and apoptosis. Here, we tabulate genes that are regulated by Ets factors and describe past, present and future strategies for the identification and validation of Ets target genes. Through definition of authentic target genes, we will begin to understand the mechanisms by which Ets factors control normal and abnormal cellular processes.

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References

  • Ahne B and Stratling WH. . 1994 J. Biol. Chem. 269: 17794–17801.

  • Ainbinder E, Bergelson S, Pinkus R and Daniel V. . 1997 Eur. J. Biochem. 243: 49–57.

  • Akbarali Y, Oettgen P, Boltax J and Libermann TA. . 1996 J. Biol. Chem. 271: 26007–26012.

  • Albanese C, Johnson J, Watanabe G, Eklund N, Vu D, Arnold A and Pestell RG. . 1995 J. Biol. Chem. 270: 23589–23597.

  • Alexander WS and Dunn AR. . 1995 Oncogene 10: 795–803.

  • Amato SF, Nakajima K, Hirano T and Chiles TC. . 1996 J. Immunol. 157: 146–155.

  • Ansieau S, Plaza S, Ferreira E, Dozier C and Stehelin D. . 1993 Genomics 18: 537–545.

  • Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, Harris MA, Hill DP, Issel-Tarver L, Kasarskis A, Lewis S, Matese JC, Richardson JE, Ringwald M, Rubin GM and Sherlock G. . 2000 Nat. Genet. 25: 25–29.

  • Aurigemma RE, Blair DG and Ruscetti SK. . 1992 J. Virol. 66: 3056–3061.

  • Avots A, Hoffmeyer A, Flory E, Cimanis A, Rapp UR and Serfling E. . 1997 Mol. Cell. Biol. 17: 4381–4389.

  • Bamberger AM, Erdmann I, Bamberger CM, Jenatschke SS and Schulte HM. . 1997 Mol. Cell. Endocrinol. 127: 71–79.

  • Bastian LS, Kwiatkowski BA, Breininger J, Danner S and Roth G. . 1999 Blood 93: 2637–2644.

  • Bastian LS, Yagi M, Chan C and Roth GJ. . 1996 J. Biol. Chem. 271: 18554–18560.

  • Beier F, Taylor AC and LuValle P. . 1999 J. Biol. Chem. 274: 30273–30279.

  • Berland R and Wortis HH. . 1998 J. Immunol. 161: 277–285.

  • Besser D, Presta M and Nagamine Y. . 1995 Cell Growth Differ. 6: 1009–1017.

  • Block KL, Shou Y and Poncz M. . 1996 Blood 88: 2071–2080.

  • Blumenthal SG, Aichele G, Wirth T, Czernilofsky AP, Nordheim A and Dittmer J. . 1999 J. Biol. Chem. 274: 12910–12916.

  • Boccia LM, Lillicrap D, Newcombe K and Mueller CR. . 1996 Mol. Cell. Biol. 16: 1929–1935.

  • Bockamp EO, Fordham JL, Gottgens B, Murrell AM, Sanchez MJ and Green AR. . 1998 J. Biol. Chem. 273: 29032–29042.

  • Bockamp EO, McLaughlin F, Murrell AM, Gottgens B, Robb L, Begley CG and Green AR. . 1995 Blood 86: 1502–1514.

  • Boehlk S, Fessele S, Mojaat A, Miyamoto NG, Werner T, Nelson EL, Schlondorff D and Nelson PJ. . 2000 Eur. J. Immunol. 30: 1102–1112.

  • Bosselut R, Duvall JF, Gegonne A, Bailly M, Hemar A, Brady J and Ghysdael J. . 1990 EMBO J. 9: 3137–3744.

  • Botelho FM, Edwards DR and Richards CD. . 1998 J. Biol. Chem. 273: 5211–5218.

  • Bottinger EP, Shelley CS, Farokhzad OC and Arnaout MA. . 1994 Mol. Cell. Biol. 14: 2604–2615.

  • Boyd KE and Farnham PJ. . 1999 Mol. Cell. Biol. 19: 8393–8399.

  • Bradford AP, Conrad KE, Wasylyk C, Wasylyk B and Gutierrez-Hartmann A. . 1995 Mol. Cell. Biol. 15: 2849–2857.

  • Bradford AP, Wasylyk C, Wasylyk B and Gutierrez-Hartmann A. . 1997 Mol. Cell. Biol. 17: 1065–1074.

  • Buras JA, Reenstra WR and Fenton MJ. . 1995 Mol. Immunol. 32: 541–554.

  • Burk O and Klempnauer KH. . 1999 Biochim. Biophys. Acta 1446: 243–252.

  • Bush A, Mateyak M, Dugan K, Obaya A, Adachi S, Sedivy J and Cole M. . 1998 Genes Dev. 12: 3797–3802.

  • Buttice G, Duterque-Coquillaud M, Basuyaux JP, Carrere S, Kurkinen M and Stehelin D. . 1996 Oncogene 13: 2297–2306.

  • Buttice G and Kurkinen M. . 1993 J. Biol. Chem. 268: 7196–7204.

  • Cardot P, Pastier D, Lacorte JM, Mangeney M, Zannis VI and Chambaz J. . 1994 Biochemistry 33: 12139–12148.

  • Carter RS and Avadhani NG. . 1994 J. Biol. Chem. 269: 4381–4387.

  • Carter RS, Bhat NK, Basu A and Avadhani NG. . 1992 J. Biol. Chem. 267: 23418–23426.

  • Carvalho M and Derse D. . 1993 J. Virol. 67: 3885–3890.

  • Castillo AI, Tolon RM and Aranda A. . 1998 Oncogene 16: 1981–1991.

  • Cederberg A, Hulander M, Carlsson P and Enerback S. . 1999 J. Biol. Chem. 274: 165–169.

  • Chan YJ, Chiou CJ, Huang Q and Hayward GS. . 1996 J. Virol. 70: 8590–8605.

  • Chang L and Thompson MA. . 1996 J. Biol. Chem. 271: 6467–6475.

  • Chapman SC, Ayala JE, Streeper RS, Culbert AA, Eaton EM, Svitek CA, Goldman JK, Tavar JM and O'Brien RM. . 1999 J. Biol. Chem. 274: 18625–18634.

  • Chen HM, Pahl HL, Scheibe RJ, Zhang DE and Tenen DG. . 1993 J. Biol. Chem. 268: 8230–8239.

  • Chen HM, Ray-Gallet D, Zhang P, Hetherington CJ, Gonzalez DA, Zhang D-E, Moreau-Gachelin F and Tenen DG. . 1995 Oncogene 11: 1549–1560.

  • Chen JH, Vercamer C, Li Z, Paulin D, Vandenbunder B and Stehelin D. . 1996 Oncogene 13: 1667–1675.

  • Chiang SY, Burli RW, Benz CC, Gawron L, Scott GK, Dervan PB and Beerman TA. . 2000 J. Biol. Chem. 275: 24246–24254.

  • Choi SG, Yi Y, Kim YS, Kato M, Chang J, Chung HW, Hahm KB, Yang HK, Rhee HH, Bang YJ and Kim SJ. . 1998 J. Biol. Chem. 273: 110–117.

  • Chotani MA, Touhalisky K and Chiu IM. . 2000 J. Biol. Chem. 275: 30432–30438.

  • Clark NM, Smith MJ, Hilfinger JM and Markovitz DM. . 1993 J. Virol. 67: 5522–5528.

  • Coffer P, de Jonge M, Mettouchi A, Binetruy B, Ghysdael J and Kruijer W. . 1994 Oncogene 9: 911–921.

  • Coles LS, Diamond P, Occhiodoro F, Vadas MA and Shannon MF. . 2000 J. Biol. Chem. 275: 14482–14493.

  • Darby TG, Meissner JD, Ruhlmann A, Mueller WH and Scheibe RJ. . 1997 Oncogene 15: 3067–3082.

  • Day RN, Liu J, Sundmark V, Kawecki M, Berry D and Elsholtz HP. . 1998 J. Biol. Chem. 273: 31909–31915.

  • De Smet C, Courtois SJ, Faraoni I, Lurquin C, Szikora JP, De Backer O and Boon T. . 1995 Immunogenetics 42: 282–290.

  • De Smet C, De Backer O, Faraoni I, Lurquin C, Brasseur F and Boon T. . 1996 Proc. Nat. Acad. Sci. USA 93: 7149–7153.

  • Deramaudt BM, Remy P and Abraham NG. . 1999 J. Cell. Biochem. 72: 311–321.

  • Deveaux S, Filipe A, Lemarchandel V, Ghysdael J, Romeo PH and Mignotte V. . 1996 Blood 87: 4678–4685.

  • Dittmer J, Gegonne A, Gitlin SD, Ghysdael J and Brady JN. . 1994 J. Biol. Chem. 269: 21428–21434.

  • Dittmer J, Gitlin SD, Reid RL and Brady JN. . 1993 J. Virol. 67: 6087–6095.

  • Dittmer J and Nordheim A. . 1998 Biochim. Biophys. Acta 1377: F1–11.

  • Dittmer J, Pise-Masison CA, Clemens KE, Choi KS and Brady JN. . 1997 J. Biol. Chem. 272: 4953–4958.

  • Donahue JP, Sugg N and Hawiger J. . 1994 Biochim Biophys Acta 1219: 228–232.

  • Donovan-Peluso M, George LD and Hassett AC. . 1994 J. Biol. Chem. 269: 1361–1369.

  • Doubeikovski A, Uzan G, Doubeikovski Z, Prandini MH, Porteu F, Gisselbrecht S and Dusanter-Fourt I. . 1997 J. Biol. Chem. 272: 24300–24307.

  • Du K, Leu JI, Peng Y and Taub R. . 1998 J. Biol. Chem. 273: 35208–35215.

  • Dube A, Akbarali Y, Sato TN, Libermann TA and Oettgen P. . 1999 Circ. Res. 84: 1177–1185.

  • Dupriez VJ, Darville MI, Antoine IV, Gegonne A, Ghysdael J and Rousseau GG. . 1993 Proc. Natl. Acad. Sci. USA 90: 8224–8228.

  • Edelman GM, Meech R, Owens GC and Jones FS. . 2000 Proc. Natl. Acad. Sci. USA 97: 3038–3043.

  • Egan BS, Lane KB and Shepherd VL. . 1999 J. Biol. Chem. 274: 9098–9107.

  • Eichbaum QG, Iyer R, Raveh DP, Mathieu C and Ezekowitz RA. . 1994 J. Exp. Med. 179: 1985–1996.

  • Eisenbeis CF, Singh H and Storb U. . 1993 Mol. Cell. Biol. 13: 6452–6461.

  • Erman B and Sen R. . 1996 EMBO J. 15: 4565–4575.

  • Ernst P, Hahm K and Smale ST. . 1993 Mol. Cell. Biol. 13: 2982–2992.

  • Ernst P, Hahm K, Trinh L, Davis JN, Roussel MF, Turck CW and Smale ST. . 1996 Mol. Cell. Biol. 16: 6121–6131.

  • Espinas ML, Roux J, Ghysdael J, Pictet R and Grange T. . 1994 Mol. Cell. Biol. 14: 4116–4125.

  • Evans RM. . 1988 Science 240: 889–895.

  • Ezashi T, Ealy AD, Ostrowski MC and Roberts RM. . 1998 Proc. Nat. Acad. Sci. USA 95: 7882–7887.

  • Fears S, Gavin M, Zhang DE, Hetherington C, Ben-David Y, Rowley JD and Nucifora G. . 1997 Proc. Nat. Acad. Sci. USA 94: 1949–1954.

  • Feinman R, Qiu WQ, Pearse RN, Nikolajczyk BS, Sen R, Sheffery M and Ravetch JV. . 1994 EMBO J. 13: 3852–3860.

  • Fenrick R, Wang L, Nip J, Amann JM, Rooney RJ, Walker-Daniels J, Crawford HC, Hulboy DL, Kinch MS, Matrisian LM and Hiebert SW. . 2000 Mol. Cell. Biol. 20: 5828–5839.

  • Flajolet M, Gegonne A, Ghysdael J, Tiollais P, Buendia MA and Fourel G. . 1997 Oncogene 15: 1103–1110.

  • Foulds CE and Hawley DK. . 1997 Nucl Acids Res. 25: 2485–2494.

  • Frampton J, Ramqvist T and Graf T. . 1996 Genes Dev. 10: 2720–2731.

  • Fujimura Y, Yamamoto H, Hamazato F and Nozaki M. . 1994 Nucl. Acids Res. 22: 613–618.

  • Fujitani Y, Nakajima K, Kojima H, Nakae K, Takeda T and Hirano T. . 1994 Biochem. Biophys. Res. Comm. 202: 1181–1187.

  • Funaoka K, Shindoh M, Yoshida K, Hanzawa M, Hida K, Nishikata S, Totsuka Y and Fujinaga K. . 1997 Biochem. Biophys Res. Comm. 236: 79–82.

  • Gagnon ML, Moy GK and Klagsbrun M. . 1999 J. Cell. Biochem. 72: 492–506.

  • Gambarotta G, Boccaccio C, Giordano S, Ando M, Stella MC and Comoglio PM. . 1996 Oncogene 13: 1911–1917.

  • Gaston K and Fried M. . 1995a Gene 157: 257–259.

  • Gaston K and Fried M. . 1995b Nucl. Acids Res. 23: 901–909.

  • Gegonne A, Bosselut R, Bailly RA and Ghysdael J. . 1993 EMBO J. 12: 1169–1178.

  • Ghozi MC, Bernstein Y, Negreanu V, Levanon D and Groner Y. . 1996 Proc. Nat. Acad. Sci. USA 93: 1935–1940.

  • Ghysdael J and Boureux A. . 1997 Oncogenes as Transcriptional Regulators, Vol. 1: Progress in Gene Expression. Yaniv M and Ghysdael J (eds). Birkhauser Verlag: Basel, pp 29–88.

  • Gitlin SD, Bosselut R, Gegonne A, Ghysdael J and Brady JN. . 1991 J. Virol. 65: 5513–5523.

  • Gomolin HI, Yamaguchi Y, Paulpillai AV, Dvorak LA, Ackerman SJ and Tenen DG. . 1993 Blood 82: 1868–1874.

  • Gory S, Dalmon J, Prandini MH, Kortulewski T, de Launoit Y and Huber P. . 1998 J. Biol. Chem. 273: 6750–6755.

  • Goto M, Masamune Y and Nakanishi Y. . 1993 Nucl. Acids Res. 21: 209–114.

  • Gramolini AO, Angus LM, Schaeffer L, Burton EA, Tinsley JM, Davies KE, Changeux JP and Jasmin BJ. . 1999 Proc. Nat. Acad. Sci. USA 96: 3223–3227.

  • Granger SW and Fan H. . 1998 J. Virol. 72: 8961–8970.

  • Grant PA, Thompson CB and Pettersson S. . 1995 EMBO J. 14: 4501–4513.

  • Graves BJ and Petersen JM. . 1998 Adv. Cancer Res. 75: 1–55.

  • Gri G, Savio D, Trinchieri G and Ma X. . 1998 J. Biol. Chem. 273: 6431–6438.

  • Grombacher T and Kaina B. . 1996 DNA and Cell Biology 15: 581–588.

  • Groupp ER and Donovan-Peluso M. . 1996 J. Biol. Chem. 271: 12423–12430.

  • Grove M and Plumb M. . 1993 Mol. Cell. Biol. 13: 5276–5289.

  • Gum R, Lengyel E, Juarez J, Chen JH, Sato H, Seiki M and Boyd D. . 1996 J. Biol. Chem. 271: 10672–10680.

  • Gunther CV and Graves BJ. . 1994 Mol. Cell. Biol. 14: 7569–7580.

  • Gupta M, Zak R, Libermann TA and Gupta MP. . 1998 Mol. Cell. Biol. 18: 7243–7258.

  • Gutman A and Wasylyk B. . 1990 EMBO J. 9: 2241–2246.

  • Halle JP, Haus-Seuffert P, Woltering C, Stelzer G and Meisterernst M. . 1997 Mol. Cell. Biol. 17: 4220–4229.

  • Hambor JE, Mennone J, Coon ME, Hanke JH and Kavathas P. . 1993 Mol. Cell. Biol. 13: 7056–7070.

  • Harris VK, Liaudet-Coopman ED, Boyle BJ, Wellstein A and Riegel AT. . 1998 J. Biol. Chem. 273: 19130–19139.

  • Hart A, Melet F, Grossfeld P, Chien K, Jones C, Tunnacliffe A, Favier R and Bernstein A. . 2000 Immunity 13: 167–177.

  • Hashimoto Y and Ware J. . 1995 J. Biol. Chem. 270: 24532–24539.

  • Henkel G and Brown MA. . 1994 Proc. Natl. Acad. Sci. USA 91: 7737–7741.

  • Hermand P, Le Pennec PY, Rouger P, Cartron JP and Bailly P. . 1996 Blood 87: 2962–2967.

  • Hewett PW, Daft EL and Murray JC. . 1998 Biochem. Biophys. Res. Commu. 252: 546–551.

  • Heydemann A, Juang G, Hennessy K, Parmacek MS and Simon MC. . 1996 Mol. Cell. Biol. 16: 1676–1686.

  • Hickey MJ and Roth GJ. . 1993 J. Biol. Chem. 268: 3438–3443.

  • Hickstein DD, Baker DM, Gollahon KA and Back AL. . 1992 Proc. Nat. Acad. Sci. USA 89: 2105–2109.

  • Higashino F, Yoshida K, Noumi T, Seiki M and Fujinaga K. . 1995 Oncogene 10: 1461–1463.

  • Hilfinger JM, Clark N, Smith M, Robinson K and Markovitz DM. . 1993 J. Virol. 67: 4448–4453.

  • Himelstein BP, Lee EJ, Sato H, Seiki M and Muschel RJ. . 1997 Oncogene 14: 1995–1998.

  • Ho IC, Bhat NK, Gottschalk LR, Lindsten T, Thompson CB, Papas TS and Leiden JM. . 1990 Science 250: 814–818.

  • Hoffmeyer A, Avots A, Flory E, Weber CK, Serfling E and Rapp UR. . 1998 J. Biol. Chem. 273: 10112–10119.

  • Hohaus S, Petrovick MS, Voso MT, Sun Z, Zhang D-E and Tenen DG. . 1995 Mol. Cell. Biol. 15: 5830–5845.

  • Holzmeister J, Ludewig B, Pauli G and Simon D. . 1993 Biochem. Biophys. Res. Commun. 197: 1229–1233.

  • Howard PW and Maurer RA. . 1995 J. Biol. Chem. 270: 20930–20936.

  • Iljin K, Dube A, Kontusaari S, Korhonen J, Lahtinen I, Oettgen P and Alitalo K. . 1999 FASEB J. 13: 377–386.

  • Inaba T, Gotoda T, Ishibashi S, Harada K, Ohsuga J-I, Ohaski K, Yazaki Y and Yamada N. . 1996 Mol. Cell. Biol. 16: 2264–2273.

  • Iwama A, Zhang P, Darlington GJ, McKercher SR, Maki R and Tenen DG. . 1998 Nucl Acids Res. 26: 3034–3043.

  • Iwamoto S, Suganuma H, Kamesaki T, Omi T, Okuda H and Kajii E. . 2000 J. Biol. Chem. 275: 27324–27331.

  • Jabrane-Ferrat N and Peterlin BM. . 1994 Mol. Cell. Biol. 14: 7314–7321.

  • Jacob KK, Ouyang L and Stanley FM. . 1995 J. Biol. Chem. 270: 27773–27779.

  • Jang SI, Karaman-Jurukovska N, Morasso MI, Steinert PM and Markova NG. . 2000 J. Biol. Chem. 275: 15295–15304.

  • Jayaraman G, Srinivas R, Duggan C, Ferreira E, Swaminathan S, Somasundaram K, Williams J, Hauser C, Kurkinen M, Dhar R, Weitzman S, Buttice G and Thimmapaya B. . 1999 J. Biol. Chem. 274: 17342–17352.

  • Johannsen E, Koh E, Mosialos G, Tong X, Kieff E and Grossman SR. . 1995 J. Virol. 69: 253–262.

  • John S, Reeves RB, Lin JX, Child R, Leiden JM, Thompson CB and Leonard WJ. . 1995 Mol. Cell. Biol. 15: 1786–1796.

  • Judde JG and Max EE. . 1992 Mol. Cell. Biol. 12: 5206–5216.

  • Kai H, Hisatsune A, Chihara T, Uto A, Kokusho A, Miyata T and Basbaum C. . 1999 J. Biol. Chem. 274: 20098–20102.

  • Kambe M, Miyamoto Y and Hayashi M. . 1998 Biochim. Biophys. Acta 1395: 209–219.

  • Kamura T, Handa H, Hamasaki N and Kitajima S. . 1997 J. Biol. Chem. 272: 11361–11368.

  • Kang R, Saito H, Ihara Y, Miyoshi E, Koyama N, Sheng Y and Taniguchi N. . 1996 J. Biol. Chem. 271: 26706–26712.

  • Kappel A, Ronicke V, Damert A, Flamme I, Risau W and Breier G. . 1999 Blood 93: 4284–4292.

  • Karantzoulis-Fegaras F, Antoniou H, Lai SL, Kulkarni G, D'Abreo C, Wong GK, Miller TL, Chan Y, Atkins J, Wang Y and Marsden PA. . 1999 J. Biol. Chem. 274: 3076–3093.

  • Kaya M, Yoshida K, Higashino F, Mitaka T, Ishii S and Fujinaga K. . 1996 Oncogene 12: 221–227.

  • Khurana TS, Rosmarin AG, Shang J, Krag TO, Das S and Gammeltoft S. . 1999 Mol. Biol. Cell. 10: 2075–2086.

  • Kienker LJ, Ghosh MR and Tucker PW. . 1998 J. Immunol. 161: 791–804.

  • Kistler B, Pfisterer P and Wirth T. . 1995 Oncogene 11: 1095–1106.

  • Ko JH, Miyoshi E, Noda K, Ekuni A, Kang R, Ikeda Y and Taniguchi N. . 1999 J. Biol. Chem. 274: 22941–22948.

  • Koizumi H, Horta MF, Youn BS, Fu KC, Kwon BS, Young JD and Liu CC. . 1993 Mol. Cell. Biol. 13: 6690–6701.

  • Kominato Y, Galson D, Waterman WR, Webb AC and Auron PE. . 1995 Mol. Cell. Biol. 15: 59–68.

  • Kondoh N, Yamada T, Kihara-Negishi F, Yamamoto M and Oikawa T. . 1998 Br. J. Cancer 78: 718–723.

  • Kramer B, Wiegmann K and Kronke M. . 1995 J. Biol. Chem. 270: 6577–6583.

  • Krehan A, Ansuini H, Bocher O, Grein S, Wirkner U and Pyerin W. . 2000 J. Biol. Chem. 275: 18327–18336.

  • Kuprash DV, Osipovich OA, Pokholok DK, Alimzhanov MB, Biragyn A, Turetskaya RL and Nedospasov SA. . 1996 J. Immunol. 156: 2465–2472.

  • Kwiatkowski BA, Bastian LS, Bauer Jr TR, Tsai S, Zielinska-Kwiatkowska AG and Hickstein DD. . 1998 J. Biol. Chem. 273: 17525–17530.

  • Lambert PF, Ludford-Menting MJ, Deacon NJ, Kola I and Doherty RR. . 1997 Mol. Biol. Cell 8: 313–323.

  • Laux G, Adam B, Strobl LJ and Moreau-Gachelin F. . 1994 EMBO J. 13: 5624–5632.

  • Leduc I and Cogne M. . 1996 Mol. Immunol. 33: 1277–1286.

  • Leiden JM, Wang CY, Petryniak B, Markovitz DM, Nabel GJ and Thompson CB. . 1992 J. Virol. 66: 5890–5897.

  • Lepage A, Uzan G, Touche N, Morales M, Cazenave JP, Lanza F and de La Salle C. . 1999 Blood 94: 3366–3380.

  • Leung S, McCracken S, Ghysdael J and Miyamoto NG. . 1993 Oncogene 8: 989–997.

  • Li AC, Guidez FR, Collier JG and Glass CK. . 1998 J. Biol. Chem. 273: 5389–5499.

  • Li R, Pei H and Papas T. . 1999a Proc. Nat. Acad. Sci. USA 96: 3876–3881.

  • Li SL, Schlegel W, Valente AJ and Clark RA. . 1999b J. Biol. Chem. 274: 32453–32460.

  • Li XR, Chong AS, Wu J, Roebuck KA, Kumar A, Parrillo JE, Rapp UR, Kimberly RP, Williams JW and Xu X. . 1999c J. Biol. Chem. 274: 35203–35210.

  • Liao WC, Ash J and Johnson LF. . 1994 Nucl. Acids Res. 22: 4044–4049.

  • Libermann TA and Baltimore D. . 1993 Mol. Cell. Biol. 13: 5957–5969.

  • Lin CS, Chang CH and Huynh T. . 1997 DNA Cell Biol. 16: 9–16.

  • Lin CS, Chen ZP, Park T, Ghosh K and Leavitt J. . 1993a J. Biol. Chem. 268: 2793–2801.

  • Lin JX, Bhat NK, John S, Queale WS and Leonard WJ. . 1993b Mol. Cell. Biol. 13: 6201–6210.

  • Littlewood TD, Hancock DC, Danielian PS, Parker MG and Evan GI. . 1995 Nucl. Acids Res. 23: 1686–1690.

  • Liu D, Pavlopoulos E, Modi W, Moschonas N and Mavrothalassitis G. . 1997 Oncogene 14: 1445–1451.

  • Liu SH and Ng SY. . 1994 Biochem. Biophys. Res. Commun. 201: 1406–1413.

  • Logan SK, Garabedian MJ, Campbell CE and Werb Z. . 1996 J. Biol. Chem. 271: 774–782.

  • Lok CN and Ponka P. . 2000 J. Biol. Chem. 275: 24185–24190.

  • Ma X, Neurath M, Gri G and Trinchieri G. . 1997 J. Biol. Chem. 272: 10389–10395.

  • Ma Y, Su Q and Tempst P. . 1998 J. Biol. Chem. 273: 8727–8740.

  • Mainguy G, Luz Montesinos M, Lesaffre B, Zevnik B, Karasawa M, Kothary R, Wurst W, Prochiantz A and Volovitch M. . 2000 Nat. Biotechnol. 18: 746–749.

  • Manzanares M, Cordes S, Kwan CT, Sham MH, Barsh GS and Krumlauf R. . 1997 Nature 387: 191–195.

  • Marchioni M, Morabito S, Salvati AL, Beccari E and Carnevali F. . 1993 Mol. Cell. Biol. 13: 6479–6489.

  • Markiewicz S, Bosselut R, Le Deist F, de Villartay JP, Hivroz C, Ghysdael J, Fischer A and de Saint Basile G. . 1996 J. Biol. Chem. 271: 14849–14855.

  • Markovitz DM, Smith MJ, Hilfinger J, Hannibal MC, Petryniak B and Nabel GJ. . 1992 J. Virol. 66: 5479–5484.

  • Maul RS, Zhang H, Reid JDT, Pedigo NG and Kaetzel DM. . 1998 J. Biol. Chem. 273: 33239–33246.

  • Maury W. . 1994 J. Virol. 68: 6270–6279.

  • Mayall TP, Sheridan PL, Montminy MR and Jones KA. . 1997 Genes Dev. 11: 887–899.

  • McCracken S, Leung S, Bosselut R, Ghysdael J and Miyamoto NG. . 1994 Oncogene 9: 3609–3615.

  • McDonough J, Francis N, Miller T and Deneris ES. . 2000 J. Biol. Chem. 275: 28962–28970.

  • McKinlay LH, Tymms MJ, Thomas RS, Seth A, Hasthorpe S, Hertzog PJ and Kola I. . 1998 J. Immunol. 161: 4098–4105.

  • McKnight RA, Spencer M, Dittmer J, Brady JN, Wall RJ and Hennighausen L. . 1995 Mol. Endocrinol. 9: 717–724.

  • McNagny KM, Sieweke MH, Doderlein G, Graf T and Nerlov C. . 1998 EMBO J. 17: 3669–3680.

  • Melotti P and Calabretta B. . 1994 J. Biol. Chem. 269: 25303–25309.

  • Minami T, Tachibana K, Imanishi T and Doi T. . 1998 Eur. J. Biochem. 258: 879–889.

  • Miyajima I, Levitt L, Hara T, Bedell MA, Copeland NG, Jenkins NA and Miyajima A. . 1995 Blood 85: 1246–1253.

  • Moreau-Gachelin F, Wendling, F, Molina T, Denis N, Titeux M, Grimber G, Briand P, Vainchenker W and Tavitian A. . 1996 Mol. Cell. Biol. 16: 2453–2463.

  • Moulton KS, Semple K, Wu H and Glass CK. . 1994 Mol. Cell. Biol. 14: 4408–4418.

  • Müller S, Sideras P, Smith CE and Santhopoulos KG. . 1996 Oncogene 13: 1955–1964.

  • Munaut C, Salonurmi T, Kontusaari S, Reponen P, Morita T, Foidart JM and Tryggvason K. . 1999 J. Biol. Chem. 274: 5588–5596.

  • Murakami K, Nomiyama H, Miura R, Follens A, Fiten P, Van Coillie E, Van Damme J and Opdenakker G. . 1997 DNA Cell Biol. 16: 173–183.

  • Nakada M, Yamashita J, Okada Y and Sato H. . 1999 J. Neuropathol. Exp. Neurol. 58: 329–334.

  • Nakajima K, Kusafuka T, Takeda T, Fujitani Y, Nakae K and Hirano T. . 1993 Mol. Cell. Biol. 13: 3027–3041.

  • Nelsen B, Tian G, Erman B, Gregoire J, Maki R, Graves B and Sen R. . 1993 Science 261: 82–86.

  • Nerlov C, Rorth P, Blasi F and Johnsen M. . 1991 Oncogene 6: 1583–1592.

  • Nguyen VT and Benveniste EN. . 2000 J. Biol. Chem. 275: 23674–23684.

  • Nimer S, Zhang J, Avraham H and Miyazaki Y. . 1996a Blood 88: 66–74.

  • Nimer SD, Zhang W, Kwan K, Wang Y and Zhang J. . 1996b Blood 87: 3694–3703.

  • Nishiyama C, Yokota T, Okumura K and Ra C. . 1999 J. Immunol. 163: 623–630.

  • Nothias JY, Weinmann R, Blangy D and Melin F. . 1993 J. Virol. 67: 3036–3047.

  • Noti JD, Reinemann C and Petrus MN. . 1996 Mol. Immunol. 33: 115–127.

  • Nozawa M, Yomogida K, Kanno N, Nonomura N, Miki T, Okuyama A, Nishimune Y and Nozaki M. . 2000 Cancer Res. 60: 1348–1352.

  • Nuchprayoon I, Meyers S, Scott LM, Suzow J, Hiebert S and Friedman AD. . 1994 Mol. Cell. Biol. 14: 5558–5568.

  • Nuchprayoon I, Shang J, Simkevich CP, Luo M, Rosmarin AG and Friedman AD. . 1999 J. Biol. Chem 274: 1085–1091.

  • Nuchprayoon I, Simkevich CP, Luo M, Friedman AD and Rosmarin AG. . 1997 Blood 89: 4546–4554.

  • Oelgeschläger M, Nuchprayoon I, Lüscher B and Friedman AD. . 1996 Mol. Cell. Biol. 16: 4717–4725.

  • Oettgen P, Alani RM, Barcinski MA, Brown L, Akbarali Y, Boltax J, Kunsch C, Munger K and Libermann TA. . 1997 Mol. Cell. Biol. 17: 4419–4433.

  • Ohbo K, Takasawa N, Ishii N, Tanaka N, Nakamura M and Sugamura K. . 1995 J. Biol. Chem. 270: 7479–7486.

  • Olsen J, Kokholm K, Troelsen JT and Laustsen L. . 1997 Biochem. J. 322: 899–908.

  • O'Prey J, Ramsay S, Chambers I and Harrison PR. . 1993 Mol. Cell. Biol. 13: 6290–6303.

  • Orlando V. . 2000 Trends Biochem. Sci. 25: 99–104.

  • Pahl HL, Scheibe RJ, Zhang DE, Chen HM, Galson DL, Maki RA and Tenen DG. . 1993 J. Biol. Chem. 268: 5014–5020.

  • Panitz F, Krain B, Hollemann T, Nordheim A and Pieler T. . 1998 EMBO J. 17: 4414–4425.

  • Pankov R, Neznanov N, Umezawa A and Oshima RG. . 1994a Mol. Cell. Biol. 14: 7744–7757.

  • Pankov R, Umezawa A, Maki R, Der CJ, Hauser CA and Oshima RG. . 1994b Proc. Nat. Acad. Sci. USA 91: 873–877.

  • Park JS, Qiao L, Gilfor D, Yang MY, Hylemon PB, Benz C, Darlington G, Firestone G, Fisher PB and Dent P. . 2000 Mol. Biol. Cell. 11: 2915–2932.

  • Pastorcic M and Das HK. . 1999 J. Biol. Chem. 274: 24297–24307.

  • Pelczar H, Albagli O, Chotteau-Lelievre A, Damour I and de Launoit Y. . 1997 Biochem. Biophys. Res. Commun. 239: 252–256.

  • Perez C, Coeffier E, Moreau-Gachelin F, Wietzerbin J and Benech PD. . 1994 Mol. Cell. Biol. 14: 5023–5031.

  • Pokholok DK, Maroulakou IG, Kuprash DV, Alimzhanov MB, Kozlov SV, Novobrantseva TI, Turetskaya RL, Green JE and Nedospasov SA. . 1995 Proc. Nat. Acad. Sci. USA 92: 674–678.

  • Pongubala JM, Van Beveren C, Nagulapalli S, Klemsz MJ, McKercher SR, Maki RA and Atchison ML. . 1993 Science 259: 1622–1625.

  • Pospelov VA, Pospelova TV and Julien JP. . 1994 Cell Growth Differ. 5: 187–196.

  • Postigo AA, Sheppard AM, Mucenski ML and Dean DC. . 1997 EMBO J. 16: 3924–3934.

  • Prandini MH, Martin F, Thevenon D and Uzan G. . 1996 Blood 88: 2062–2070.

  • Punturieri A, Shirakata Y, Bovolenta C, Kikuchi G and Coligan JE. . 1993 J. Immunol. 150: 139–150.

  • Quan T and Fisher GJ. . 1999 J. Biol. Chem. 274: 28566–28574.

  • Rao E, Dang W, Tian G and Sen R. . 1997 J. Biol. Chem. 272: 6722–6732.

  • Rao S, Garrett-Sinha LA, Yoon J and Simon MC. . 1999 J. Biol. Chem. 274: 34245–34252.

  • Ratajczak MZ, Perrotti D, Melotti P, Powzaniuk M, Calabretta B, Onodera K, Kregenow DA, Machalinski B and Gewirtz AM. . 1998 Blood 91: 1934–1946.

  • Ray-Gallet D, Mao C, Tavitian A and Moreau-Gachelin F. . 1995 Oncogene 11: 303–313.

  • Rebay I, Chen F, Hsiao F, Kolodziej PA, Kuang BH, Laverty T, Suh C, Voas M, Williams A and Rubin GM. . 2000 Genetics 154: 695–712.

  • Reddy MA, Yang BS, Yue X, Barnett CJ, Ross IL, Sweet MJ, Hume DA and Ostrowski MC. . 1994 J. Exp. Med. 180: 2309–2319.

  • Rehli M, Lichanska A, Cassady AI, Ostrowski MC and Hume DA. . 1999 J. Immunol. 162: 1559–1565.

  • Rellahan BL, Jensen JP, Howcroft TK, Singer DS, Bonvini E and Weissman AM. . 1998 J. Immunol. 160: 2794–2801.

  • Rhodes K and Oshima RG. . 1998 J. Biol. Chem. 273: 26534–26542.

  • Ried S, Jager C, Jeffers M, Vande Woude GF, Graeff H, Schmitt M and Lengyel E. . 1999 J. Biol. Chem. 274: 16377–16386.

  • Ritchie KA, Aprikyan AA, Bowen-Pope DF, Norby-Slycord CJ, Conyers S, Bartelmez S, Sitnicka EH and Hickstein DD. . 1999 Leukemia 13: 1790–1803.

  • Rius C, Smith JD, Almendro N, Langa C, Botella LM, Marchuk DA, Vary CP and Bernabeu C. . 1998 Blood 92: 4677–4690.

  • Rivera RR, Stuiver MH, Steenbergen R and Murre C. . 1993 Mol. Cell. Biol. 13: 7163–7169.

  • Robinson L, Panayiotakis A, Papas TS, Kola I and Seth A. . 1997 Proc. Nat. Acad. Sci. USA 94: 7170–7175.

  • Rodrigo I, Cato AC and Cano A. . 1999 Exp. Cell Res. 248: 358–371.

  • Roebuck KA, Rahman A, Lakshminarayanan V, Janakidevi K and Malik AB. . 1995 J. Biol. Chem. 270: 18966–18974.

  • Rorth P, Nerlov C, Blasi F and Johnsen M. . 1990 Nucl. Acids Res. 18: 5009–5017.

  • Rosen GD, Barks JL, Iademarco MF, Fisher RJ and Dean DC. . 1994 J. Biol. Chem. 269: 15652–15660.

  • Rosmarin AG, Caprio D, Levy R and Simkevich C. . 1995a Proc. Nat. Acad. Sci. USA 92: 801–805.

  • Rosmarin AG, Caprio DG, Kirsch DG, Handa H and Simkevich CP. . 1995b J. Biol. Chem. 270: 23627–23633.

  • Rosmarin AG, Luo M, Caprio DG, Shang J and Simkevich CP. . 1998 J. Biol. Chem. 273: 13097–13103.

  • Ross IL, Yue X, Ostrowski MC and Hume DA. . 1998 J. Biol. Chem. 273: 6662–6669.

  • Rubin GM and Lewis EB. . 2000 Science 287: 2216–2218.

  • Rushton JJ, Zorich GP, Stolc V and Neudorf SM. . 1997 Eur. J. Biochem. 245: 768–773.

  • Sadasivan E, Cedeno MM and Rothenberg SP. . 1994 J. Biol. Chem. 269: 4725–4735.

  • Salmon P, Giovane A, Wasylyk B and Klatzmann D. . 1993 Proc. Natl. Acad. Sci. USA 90: 7739–7743.

  • Sapi E, Flick MB, Rodov S and Kacinski BM. . 1998 Cancer Res. 58: 1027–1033.

  • Sapru MK, Florance SK, Kirk C and Goldman D. . 1998 Proc. Nat. Acad. Sci. USA 95: 1289–1294.

  • Sark MW, Fischer DF, de Meijer E, van de Putte P and Backendorf C. . 1998 J. Biol. Chem. 273: 24683–24692.

  • Sato M, Morii E, Komori T, Kawahata H, Sugimoto M, Terai K, Shimizu H, Yasui T, Ogihara H, Yasui N, Ochi T, Kitamura Y, Ito Y and Nomura S. . 1998 Oncogene 17: 1517–1525.

  • Savoysky E, Mizuno T, Sowa Y, Watanabe H, Sawada J, Nomura H, Ohsugi Y, Handa H and Sakai T. . 1994 Oncogene 9: 1839–1846.

  • Sawada J, Simizu N, Suzuki F, Sawa C, Goto M, Hasegawa M, Imai T, Watanabe H and Handa H. . 1999 J. Biol. Chem. 274: 35475–35482.

  • Schaeffer L, Duclert N, Huchet-Dymanus M and Changeux JP. . 1998 EMBO J. 17: 3078–3090.

  • Schlaeger TM, Bartunkova S, Lawitts JA, Teichmann G, Risau W, Deutsch U and Sato TN. . 1997 Proc. Nat. Acad. Sci. USA 94: 3058–3063.

  • Schwachtgen JL, Janel N, Barek L, Duterque-Coquillaud M, Ghysdael J, Meyer D and Kerbiriou-Nabias D. . 1997 Oncogene 15: 3091–3102.

  • Schwarzenbach H, Newell JW and Matthias P. . 1995 J. Biol. Chem. 270: 898–907.

  • Scott GK, Daniel JC, Xiong X, Maki RA, Kabat D and Benz CC. . 1994 J. Biol. Chem. 269: 19848–19858.

  • Sementchenko VI, Schweinfest CW, Papas TS and Watson DK. . 1998 Oncogene 17: 2883–2888.

  • Serdobova I, Pla M, Reichenbach P, Sperisen P, Ghysdael J, Wilson A, Freeman J and Nabholz M. . 1997 J. Exp. Med. 185: 1211–1221.

  • Seth A, Robinson L, Panayiotakis A, Thompson DM, Hodge DR, Zhang XK, Watson DK, Ozato K and Papas TS. . 1994 Oncogene 9: 469–477.

  • Seth A, Robinson L, Thompson DM, Watson DK and Papas TS. . 1993 Oncogene 8: 1783–1790.

  • Sevilla L, Aperlo C, Dulic V, Chambard JC, Boutonnet C, Pasquier O, Pognonec P and Boulukos KE. . 1999 Mol. Cell. Biol. 19: 2624–2634.

  • Shapiro LH. . 1995 J. Biol. Chem. 270: 8763–8771.

  • Shelley CS, Farokhzad OC and Arnaout MA. . 1993 Proc. Natl. Acad. Sci. USA 90: 5364–5368.

  • Shin MK and Koshland ME. . 1993 Genes Dev. 7: 2006–2015.

  • Shirasaki F, Makhulf HA, LeRoy C, Watson DK and Trojanowska M. . 1999 Oncogene 18: 7755–7764.

  • Sideras P, Muller S, Shiels H, Jin H, Khan WN, Nilsson L, Parkinson E, Thomas JD, Branden L, Larsson I and et al. 1994 J. Immunol. 153: 5607–5617.

  • Sieweke MH, Tekotte H, Jarosch U and Graf T. . 1998 EMBO J. 17: 1728–1739.

  • Smith Jr MF, Carl VS, Lodie T and Fenton MJ. . 1998 J. Biol. Chem. 273: 24272–24279.

  • Soldatenkov VA, Albor A, Patel BK, Dreszer R, Dritschilo A and Notario V. . 1999 Oncogene 18: 3954–3962.

  • Spyropoulos DD, Pharr PN, Lavenburg KR, Jackers P, Papas TS, Ogawa M and Watson DK. . 2000 Mol. Cell. Biol. 20: 5643–5652.

  • Stacey KJ, Fowles LF, Colman MS, Ostrowski MC and Hume DA. . 1995 Mol. Cell. Biol. 15: 3430–3441.

  • Starck J, Doubeikovski A, Sarrazin S, Gonnet C, Rao G, Skoultchi A, Godet J, Dusanter-Fourt I and Morle F. . 1999 Mol. Cell. Biol. 19: 121–135.

  • Steer JH, Kroeger KM, Abraham LJ and Joyce DA. . 2000 J. Biol. Chem. 275: 18432–18440.

  • Stutz AM and Woisetschlager M. . 1999 J. Immunol. 163: 4383–4391.

  • Sullivan J, Feeley B, Guerra J and Boxer LM. . 1997 J. Biol. Chem. 272: 1943–1949.

  • Sumarsono SH, Wilson TJ, Tymms MJ, Venter DJ, Corrick CM, Kola R, Lahoud MH, Papas TS, Seth A and Kola I. . 1996 Nature 379: 534–537.

  • Suzuki S, Kumatori A, Haagen IA, Fujii Y, Sadat MA, Jun HL, Tsuji Y, Roos D and Nakamura M. . 1998 Proc. Natl. Acad. Sci. USA 95: 6085–6090.

  • Tajima A, Miyamoto Y, Kadowaki H and Hayashi M. . 2000 Biochim. Biophys. Acta 1492: 377–384.

  • Takaoka AS, Yamada T, Gotoh M, Kanai Y, Imai K and Hirohashi S. . 1998 J. Biol. Chem. 273: 33848–33855.

  • Tamir A, Howard J, Higgins RR, Li YJ, Berger L, Zacksenhaus E, Reis M and Ben-David Y. . 1999 Mol. Cell. Biol. 19: 4452–4464.

  • Tanimura A, Teshima H, Fujisawa J and Yoshida M. . 1993 J. Virol. 67: 5375–5382.

  • Taylor JM, Davies JD and Peterson CA. . 1995 J. Biol. Chem. 270: 2535–2540.

  • Thomas RS, Tymms MJ, McKinlay LH, Shannon MF, Seth A and Kola I. . 1997 Oncogene 14: 2845–2855.

  • Thomas RS, Tymms MJ, Seth A, Shannon MF and Kola I. . 1995 Oncogene 11: 2135–2143.

  • Thompson AA, Wood Jr WJ, Gilly MJ, Damore MA, Omori SA and Wall R. . 1996 Blood 87: 666–673.

  • Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B and et al. 1992 Mol. Cell. Biol. 12: 1043–1053.

  • Tokino T, Thiagalingam S, el-Deiry WS, Waldman T, Kinzler KW and Vogelstein B. . 1994 Hum. Mol. Genet. 3: 1537–1542.

  • Tommasi S and Pfeifer GP. . 1995 Mol. Cell. Biol. 15: 6901–6913.

  • Townsend KJ, Zhou P, Qian L, Bieszczad CK, Lowrey CH, Yen A and Craig RW. . 1999 J. Biol. Chem. 274: 1801–1813.

  • Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF and Goldfeld AE. . 2000 Mol. Cell. Biol. 20: 6084–6094.

  • Turque N, Buttice G, Beuscart A, Stehelin D, Crepieux P and Desbiens X. . 1997 Int. J. Dev. Biol. 41: 103–109.

  • Umezawa A, Yamamoto H, Rhodes K, Klemsz MJ, Maki RA and Oshima RG. . 1997 Mol. Cell. Biol. 17: 4885–4894.

  • van Dijk TB, Baltus B, Caldenhoven E, Handa H, Raaijmakers JA, Lammers JW, Koenderman L and de Groot RP. . 1998 Blood 92: 3636–3646.

  • Van Lint C, Ghysdael J, Paras Jr P, Burny A and Verdin E. . 1994 J. Virol. 68: 2632–2648.

  • Venanzoni MC, Robinson LR, Hodge DR, Kola I and Seth A. . 1996 Oncogene 12: 1199–1204.

  • Villena JA, Martin I, Vinas O, Cormand B, Iglesias R, Mampel T, Giralt M and Villarroya F. . 1994 J. Biol. Chem. 269: 32649–32654.

  • Virbasius JV and Scarpulla RC. . 1991 Mol. Cell. Biol. 11: 5631–5638.

  • von der Ahe D, Nischan C, Kunz C, Otte J, Knies U, Oderwald H and Wasylyk B. . 1993 Nucl Acids Res. 21: 5636–5643.

  • Voo KS and Skalnik DG. . 1999 Blood 93: 3512–3520.

  • Wakiya K, Begue A, Stehelin D and Shibuya M. . 1996 J. Biol. Chem. 271: 30823–30828.

  • Wang CY, Bassuk AG, Boise LH, Thompson CB, Bravo R and Leiden JM. . 1994a Mol. Cell. Biol. 14: 1153–1159.

  • Wang LG, Liu XM, Li ZR, Denstman S and Bloch A. . 1994b Cell Growth Differ. 5: 1243–1251.

  • Wasylyk C, Gutman A, Nicholson R and Wasylyk B. . 1991 EMBO J. 10: 1127–1134.

  • Watabe T, Yoshida K, Shindoh M, Kaya M, Fujikawa K, Sato H, Seiki M, Ishii S and Fujinaga K. . 1998 Int. J. Cancer 77: 128–137.

  • Watson DK, Ascione R and Papas TS. . 1990 Crit. Rev. Oncog. 1: 409–436.

  • Watson DK, Kitching R, Vary C, Kola I and Seth A. . 2000 Meth. Mol. Biol. 130: 1–11.

  • Watson DK, Li R, Sementchenko VI, Mavrothalassitis G and Seth A. . 2001 The ETS genes, Bertino, J. R. (Ed). Encyclopedia of Cancer. Academic Press.

  • Welte T, Garimorth K, Philipp S, Jennewein P, Huck C, Cato AC and Doppler W. . 1994 Eur. J. Biochem. 223: 997–1006.

  • Wen SC, Ku DH, De Luca A, Claudio PP, Giordano A and Calabretta B. . 1995 Exp. Cell Res. 217: 8–14.

  • Wilkinson NC and Navarro J. . 1999 J. Biol. Chem. 274: 438–443.

  • Wotton D, Prosser HM and Owen MJ. . 1993 Leukemia 7: S55–S60.

  • Yamamoto H, Flannery ML, Kupriyanov S, Pearce J, McKercher SR, Henkel GW, Maki RA, Werb Z and Oshima RG. . 1998 Genes Dev. 12: 1315–1326.

  • Yan S, Berquin IM, Troen BR and Sloane BF. . 2000 DNA Cell Biol. 19: 79–91.

  • Yan SF, Lu J, Zou YS, Soh-Won J, Cohen DM, Buttrick PM, Cooper DR, Steinberg SF, Mackman N, Pinsky DJ and Stern DM. . 1999 J. Biol. Chem. 274: 15030–15040.

  • Yang C, Shapiro LH, Rivera M, Kumar A and Brindle PK. . 1998a Mol. Cell. Biol. 18: 2218–2229.

  • Yang Z, Boffelli D, Boonmark N, Schwartz K and Lawn R. . 1998b J. Biol. Chem. 273: 891–897.

  • Yang Z, Wara-Aswapati N, Chen C, Tsukada J and Auron PE. . 2000 J. Biol. Chem. 275: 21272–21277.

  • Ying H, Chang JF and Parnes JR. . 1998 J. Immunol. 160: 2287–2296.

  • Yoganathan T, Cowie A, Hassell JA and Sells BH. . 1992 Eur. J. Biochem. 207: 195–200.

  • Yokomori N, Kobayashi R, Moore R, Sueyoshi T and Negishi M. . 1995 Mol. Cell. Biol. 15: 5355–5362.

  • Youn BS, Kim KK and Kwon BS. . 1996 J. Immunol. 157: 3499–3509.

  • Zhang C, Gadue P, Scott E, Atchison M and Poncz M. . 1997a J. Biol. Chem. 272: 26236–26246.

  • Zhang DE, Hetherington CJ, Chen HM and Tenen DG. . 1994 Mol. Cell. Biol. 14: 373–381.

  • Zhang DE, Hohaus S, Voso MT, Chen HM, Smith LT, Hetherington CJ and Tenen DG. . 1996 Curr. Topics Microbiol. Immunol. 211: 137–147.

  • Zhang L, Eddy A, Teng Y-T, Fritzler M, Kluppel M, Melet F and Bernstein A. . 1995 Mol. Cell. Biol. 15: 6961–6970.

  • Zhang M, Maass N, Magit D and Sager R. . 1997b Cell Growth Differ. 8: 179–186.

  • Zhang M, Magit D and Sager R. . 1997c Proc. Nat. Acad. Sci. USA 94: 5673–5678.

  • Zhang Y and Lichtenheld MG. . 1997 J. Immunol. 158: 1734–1741.

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Acknowledgements

This work is dedicated to Takis S Papas, a friend, valued colleague and mentor. This work was supported in part by grants from the DOD [N00014-96-1-1298] and NCI [PO1 CA78582].

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  1. Center for Molecular and Structural Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29403, South Carolina, USA

    Victor I Sementchenko & Dennis K Watson

  2. Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29403, South Carolina, USA

    Dennis K Watson

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Sementchenko, V., Watson, D. Ets target genes: past, present and future. Oncogene 19, 6533–6548 (2000). https://doi.org/10.1038/sj.onc.1204034

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