This Article contains an error in the Figure legend of Figure 1. The correct Figure legend is given below:
Figure 1. Generation of the mice with liver-specific KrasG12D expression and Pten deletion. (A) Strategy to generate the compound mice. Conditional KrasG12D knockin mice and conditional Pten knockout mice were crossed with Alb-Cre mice. (B–D) Gross appearance of an AKPP mouse at 8 weeks of age. Liver was enlarged and jaundice was observed, sometimes accompanying hemorrhagic ascites (B). Diffuse and firm tumorous lesions were observed in the liver (C,D). (E) Survival of AKPP (n = 23), AKP (n = 11), and AK (n = 9) mice. (F–I) H&E staining of the liver of the AKPP mice at 3 weeks, 5weeks, and 8 weeks of age. Normal bile duct formation (arrow) in the liver of a 3 week-old mouse (F). Bile duct hyperplasia in the liver of a 5 week-old mouse (G). A highly differentiated cholangiocarcinoma-like lesion in the liver of an 8 week-old mouse (H). A moderately differentiated cholangiocarcinoma-like lesion in in the liver of an 8 week-old mouse (I). Bars: 100μm.
Additional information
The online version of the original article can be found at 10.1038/srep23899
Rights and permissions
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
About this article
Cite this article
Ikenoue, T., Terakado, Y., Nakagawa, H. et al. Correction: Corrigendum: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion. Sci Rep 7, 39567 (2017). https://doi.org/10.1038/srep39567
Published:
DOI: https://doi.org/10.1038/srep39567
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
