Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Structure of Thermolysin

Abstract

Results of the chemical and X-ray analyses are combined to locate the active site and the calcium binding sites.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Titani, K., Hermodson, M. A., Ericsson, L. H., Walsh, K. A., and Neurath, H., Nature New Biology, 238, 35 (1972).

    Article  CAS  Google Scholar 

  2. Matthews, B. W., Jansonius, J. N., Colman, P. M., Schoenborn, B. P., and Dupourque, D., Nature New Biology, 238, 37 (1972).

    Article  CAS  Google Scholar 

  3. Kendrew, J. C., Watson, H. C., Strandberg, B. E., Dickerson, R. E., Phillips, D. C., and Shore, V. C., Nature, 190, 666 (1961).

    Article  CAS  Google Scholar 

  4. Edmundson, A. B., Nature, 205, 883 (1965).

    Article  CAS  Google Scholar 

  5. Lipscomb, W. N., Hartsuck, J. A., Quiocho, F. A., and Reeke, G. N., Proc. US Nat. Acad. Set., 64, 28 (1969).

    Article  CAS  Google Scholar 

  6. Lipscomb, W. N., Reeke, G. N., Hartsuck, J. A., Quiocho, F. A., and Bethge, P. H., Phil. Trans. Roy. Soc., B, 257, 177 (1970).

    Article  CAS  Google Scholar 

  7. Blow, D. M., and Steitz, T. A., Ann. Rev. Biochem., 39, 63 (1970).

    Article  CAS  Google Scholar 

  8. Kraut, J., Robertus, J. D., Birktoft, J. J., Alden, R. A., Wilcox, P. E., and Powers, J. C., Cold Spring Harbor Symp. Quant. Biol., 36 (in the press).

  9. Wright, C. S., Alden, R. A., and Kraut, J., Nature, 111, 235 (1969).

    Article  Google Scholar 

  10. Endo, S., J. Fermentation Tech., 40, 346 (1962).

    CAS  Google Scholar 

  11. Latt, S. A., Holmquist, B., and Vallee, B. L., Biochem. Biophys. Res. Commun., 37, 333 (1969).

    Article  CAS  Google Scholar 

  12. Feder, J., Garrett, L. R., and Wildi, B. S., Biochemistry (in the press).

  13. Drucker, H., Borchers, S., and Yang, J. T., Fed. Proc, 29, Biochem. Abstr. 2361 (1970).

  14. Colman, P. M., Weaver, L. H., and Matthews, B. W., Biochem. Biophys. Res. Commun., 46, 1999 (1972).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MATTHEWS, B., COLMAN, P., JANSONIUS, J. et al. Structure of Thermolysin. Nature New Biology 238, 41–43 (1972). https://doi.org/10.1038/newbio238041a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/newbio238041a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing