Obesity is a considerable threat to the future health of our children. Data from a large prospective cohort study have now led to the generation of a simple tool that can be used in the neonatal period to identify babies at the highest risk of developing obesity later in life. Will this tool prove useful or not?
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References
Han, J. C., Lawlor, D. A. & Kimm, S. Y. Childhood obesity. Lancet 375, 1737–1748 (2010).
Morandi, A. et al. Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts. PLoS ONE 7, e49919 (2012).
Brisbois, T. D., Farmer, A. P. & McCargar, L. J. Early markers of adult obesity: a review. Obes. Rev. 13, 347–367 (2012).
Li, S. et al. Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies. Am. J. Clin. Nutr. 91, 184–190 (2010).
Noble, D., Mathur, R., Dent, T., Meads, C. & Greenhalgh, T. Risk models and scores for type 2 diabetes: systematic review. BMJ 343, d7163 (2011).
Juonala, M. et al. Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring. J. Pediatr. http://dx.doi.org/10.1016/j.jpeds.2012.10.062.
Juonala, M. et al. Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study. J. Clin. Endocrinol. Metab. 96, E1542–E1549 (2011).
Sabin, M. A. et al. New directions in childhood obesity research: how a comprehensive biorepository will allow better prediction of outcomes. BMC Med. Res. Methodol. 10, 100 (2010).
Juonala, M. et al. Childhood adiposity, adult adiposity, and cardiovascular risk factors. N. Engl. J. Med. 365, 1876–1885 (2011).
Shihab, H. M. et al. Body mass index and risk of incident hypertension over the life course: the Johns Hopkins precursors study. Circulation 126, 2983–2989 (2012).
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Sabin, M., Juonala, M. Predicting risk of later obesity from the first day of life. Nat Rev Endocrinol 9, 136–138 (2013). https://doi.org/10.1038/nrendo.2013.16
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DOI: https://doi.org/10.1038/nrendo.2013.16