The consequences of fluid administration and the maintenance of fluid balance, despite their ubiquity in critical care, remain a topic of much debate among clinicians. Emerging evidence suggests that fluid administration and a positive fluid balance can be harmful in a number of conditions, including acute kidney injury.
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Glassford, N., Bellomo, R. Fluid therapy in acute kidney injury: the FACTTs. Nat Rev Nephrol 7, 305–306 (2011). https://doi.org/10.1038/nrneph.2011.57
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DOI: https://doi.org/10.1038/nrneph.2011.57
