Nature Reviews Neurology 13, 612–623 (2017)

In the version of this article originally published online, Figure 1 incorrectly labelled the main Aβ molecule in the peripheral pool as Aβ42 instead of Aβ40. This error has been corrected in the HTML and PDF versions of the article.

Additionally, in the printed version of this article, the 'published online' date was given as 28 September 2017. However, because of a technical problem, the article was actually published online on 29 September 2017. This is correct in the HTML and PDF versions of the article.