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Looking forward, looking back—10 years in urology

Abstract

When Nature Reviews Urology launched in 2004, the field of urology was vastly different to that which we work in today, and the past 10 years have seen the field change immensely. As a specialty on the forefront of cutting-edge innovation, urologists are often the first to embrace new technologies and ideas. In this Viewpoint, members of the Nature Reviews Urology advisory board were asked what they thought was the most important change, issue or innovation in urology in the past 10 years, and what they expected to be the most important in the next decade. Here are their opinions.

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References

  1. Bochinski, D. et al. The effect of neural embryonic stem cell therapy in a rat model of cavernosal nerve injury. BJU Int. 94, 904–909 (2004).

    Article  Google Scholar 

  2. Yiou, R. et al. Intra-cavernous injection of bone marrow stem cells is well tolerated and improve erectile function in patients with post-prostatectomy erectile dysfunction: Preliminary results of a phase I-II clinical trial. Abstract 599. Presented at the 29th Annual EAU Congress (2014).

  3. Wilt, T. J. et al. Radical prostatectomy versus observation for localized prostate cancer. N. Engl. J. Med. 367, 203–213 (2012).

    Article  CAS  Google Scholar 

  4. Bul, M. et al. Active surveillance for low-risk prostate cancer worldwide: the PRIAS study. Eur. Urol. 63, 597–603 (2013).

    Article  Google Scholar 

  5. Sridhar, A. N. et al. Image-guided robotic interventions for prostate cancer. Nat. Rev. Urol. 10, 452–462 (2013).

    Article  Google Scholar 

  6. Lawrentschuk, N. & Klotz, L. Active surveillance for low-risk prostate cancer: an update. Nat. Rev. Urol. 8, 312–320 (2011).

    Article  Google Scholar 

  7. Varela, I. et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469, 539–542 (2011).

    Article  CAS  Google Scholar 

  8. The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 499, 43–49 (2013).

  9. Centers for Disease Control and Prevention. Assisted Reproductive Technology [online], (2014).

  10. Baillargeon, J. et al. Trends in androgen prescribing in the United States, 2001 to 2011. JAMA Intern. Med. 173, 1465–1466 (2013).

    Article  Google Scholar 

  11. International Telecommunication Union. The world in 2013: ICT facts and figures [online], (2014).

  12. Agarwal, A. et al. Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study. Fertil. Steril. 89, 124–128 (2008).

    Article  Google Scholar 

  13. US Food and Drug Administration. Outpatient Prescription Opioid Utilization in the U. S. Years 2000–2009 [online], (2014).

  14. Fronczak, C. M., Kim, E. D. & Barqawi, A. B. The insults of illicit drug use on male fertility. J. Androl. 33, 515–528 (2012).

    Article  CAS  Google Scholar 

  15. Barazani, Y. et al. Lifestyle, environment, and reproductive health. Urol. Clin. N. Am. 41, 55–66 (2013).

    Article  Google Scholar 

  16. Moyer, V. A. U.S. Preventive Services Task Force Screening for prostate cancer: U.S. Preventive Services Task Force recommendation statement. Ann. Intern. Med. 157, 120–134 (2012).

    Article  Google Scholar 

  17. Barry, M. J., Gallagher, P. M., Skinner, J. S. & Fowler, F. J. Jr. Adverse effects of robotic-assisted laparoscopic versus open radical retropubic prostatectomy among a nationwide sample of Medicare-age men. J. Clin. Oncol. 30, 513–513 (2012).

    Article  Google Scholar 

  18. Tewari, A. et al. Positive surgical margin and perioperative complication rates of primary surgical treatments for prostate cancer: a systematic review and meta-analysis comparing retropubic, laparoscopic, and robotic prostatectomy. Eur. Urol. 62, 1–15 (2012).

    Article  Google Scholar 

  19. Gandaglia, G. et al. Comparative effectiveness of robot-assisted and open radical prostatectomy in the postdissemination era. J. Clin. Oncol. 32, 1419–1426 (2014).

    Article  Google Scholar 

  20. Tannock, I. F. et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N. Engl. J. Med. 351, 1502–1512 (2004).

    Article  CAS  Google Scholar 

  21. de Bono, J. S. et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet 376, 1147–1154 (2010).

    Article  CAS  Google Scholar 

  22. Attard, G. et al. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J. Clin. Oncol. 27, 3742–3748 (2008).

    Article  Google Scholar 

  23. Scher, H. I. et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. N. Engl. J. Med. 367, 1187–1197 (2012).

    Article  CAS  Google Scholar 

  24. Parker, C. et al. Alpha emitter radium-223 and survival in metastatic prostate cancer. N. Engl. J. Med. 369, 213–223 (2013).

    Article  CAS  Google Scholar 

  25. Stenzl, A. et al. Treatment of muscle-invasive and metastatic bladder cancer: update of the EAU guidelines. Eur. Urol. 59, 1009–1018 (2011).

    Article  CAS  Google Scholar 

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Acknowledgements

H.N. would like to thank Doron Stember for his assistance with his contribution to this article.

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Correspondence to Maarten Albersen, Rufus Cartwright, Peter Choyke, S. Larry Goldenberg, Howard Goldman, Nathan Lawrentschuk, W. Marston Linehan, Declan Murphy, Harris Nagler, Peter Scardino, Linda Shortliffe, Arnulf Stenzl or Dan Theodorescu.

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Competing interests

H. G. declares that he is a member of the speakers' bureau for Allergan, Medtronic and Uroplasty, and that he has acted as a consultant for Allergan, Astellas, Medtronic and Uroplasty. P.S. declares that he is a scientific advisor to OPKO Diagnostics, who are developing a commercial assay for the 4KScore® developed at Memorial Sloan–Kettering. A.S. declares that has acted as a consultant for Alere, and as a speaker and consultant for Ipsen and Janssen. His institution receives research grants from Amgen, Immatics Biotechnologies GmbH, Karl Storz and Novartis, and is involved in clinical studies with Bayer, CureVac, Immatics Biotechnologies GmbH and Johnson & Johnson. The other authors declare no competing interests.

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Albersen, M., Cartwright, R., Choyke, P. et al. Looking forward, looking back—10 years in urology. Nat Rev Urol 11, 649–655 (2014). https://doi.org/10.1038/nrurol.2014.263

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