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A master of its sulfate

The key step in the biosynthesis of a sulfated glycolipid in the disease-causing bacterium Mycobacterium tuberculosis is revealed by the discovery of the sulfotransferase that installs the sulfate moiety.

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Figure 1: Making sulfolipid-1 (SL-1).
Figure 2
Figure 3: Proposed biosynthesis of SL-1.

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Williams, S., Davies, G. A master of its sulfate. Nat Struct Mol Biol 11, 686–687 (2004). https://doi.org/10.1038/nsmb0804-686

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