Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Lessons learnt from the emergence of Zika virus

Looking back at how Zika virus emergence was handled during and after the 2015–2016 outbreak will be important for assessing how well multiple relevant stakeholders were integrated to mount a response, and can provide the groundwork to better cope with emerging infections in the future.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

References

  1. Macnamara, F. N. Trans. R. Soc. Trop. Med. Hyg. 48, 139–145 (1954).

    Article  CAS  Google Scholar 

  2. Duffy, M. R. et al. N. Engl. J. Med. 360, 2536–2543 (2009).

    Article  CAS  Google Scholar 

  3. Musso, D. et al. Euro Surveill. 19, 20761 (2014).

    Article  Google Scholar 

  4. Cauchemez, S. et al. Lancet 387, 2125–2132 (2016).

    Article  Google Scholar 

  5. Zika Cumulative Cases (PAHO, WHO, accessed 1 July 2018); https://go.nature.com/2tNktxY

  6. Driggers, R. W. et al. N. Engl. J. Med. 374, 2142–2151 (2016).

    Article  CAS  Google Scholar 

  7. Mlakar, J. et al. N. Engl. J. Med. 374, 951–958 (2016).

    Article  CAS  Google Scholar 

  8. Hoen, B. et al. N. Engl. J. Med. 378, 985–994 (2018).

    Article  Google Scholar 

  9. Honein, M. A. et al. JAMA 317, 59–68 (2017).

    Article  Google Scholar 

  10. Cao-Lormeau, V. M. et al. Lancet 387, 1531–1539 (2016).

    Article  Google Scholar 

  11. WHO statement on the first meeting of the International Health Regulations (2005) (IHR 2005) Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations. World Health Organization (1 February 2016); https://go.nature.com/2NiMKo2

  12. Zika: Commission activities in the area of Zika (European Commission, 2016); https://go.nature.com/2tRKyMb

  13. Gladwyn-Ng, I. et al. Nat. Neurosci. 21, 63–71 (2018).

    Article  CAS  Google Scholar 

  14. Xu, M. et al. Nat. Med. 22, 1101–1107 (2016).

    Article  CAS  Google Scholar 

  15. Weaver, S. C., Charlier, C., Vasilakis, N. & Lecuit, M. Annu. Rev. Med. 69, 395–408 (2018).

    Article  CAS  Google Scholar 

  16. Laguesse, S. et al. Dev. Cell 35, 553–567 (2015).

    Article  CAS  Google Scholar 

  17. Dang, J. et al. Cell Stem Cell 19, 258–265 (2016).

    Article  CAS  Google Scholar 

  18. Li, Y. et al. Cell Stem Cell 3, 385–396 (2016).

    Google Scholar 

  19. Qian, X. et al. Cell 165, 1238–1254 (2016).

    Article  CAS  Google Scholar 

  20. Watanabe, M. et al. Cell. Rep. 21, 517–532 (2017).

    Article  CAS  Google Scholar 

  21. Aliota, M. T. et al. Antiviral Res. 144, 223–246 (2017).

    Article  CAS  Google Scholar 

  22. Corman, V. M. et al. Bull. World Health Organ. 94, 880–892 (2016).

    Article  Google Scholar 

  23. Poland, G. A. et al. Lancet Infect. Dis. 18, 211–219 (2018).

    Article  Google Scholar 

  24. Subudhi, B. B., Chattopadhyay, S., Mishra, P. & Kumar, A. Viruses 10, E235 (2018).

    Article  Google Scholar 

  25. Yuan, L. et al. Science 358, 933–936 (2017).

    Article  CAS  Google Scholar 

  26. Coelho, F. C. et al. Int. J. Infect. Dis. 51, 128–132 (2016).

    Article  Google Scholar 

  27. McCarthy, M. BMJ 352, i720 (2016).

    Article  Google Scholar 

  28. Duggal, N. K. et al. Cell. Rep. 18, 1751–1760 (2017).

    Article  CAS  Google Scholar 

  29. Tang, W. W. et al. Cell. Rep. 17, 3091–3098 (2016).

    Article  CAS  Google Scholar 

  30. Moreira, J., Peixoto, T. M., Siqueira, A. M. & Lamas, C. C. Clin. Microbiol. Infect. 23, 296–305 (2017).

    Article  CAS  Google Scholar 

  31. Moreira, J., Bressan, C. S., Brasil, P. & Siqueira, A. M. Clin. Microbiol. Infect. 24, 827–835 (2018).

  32. Martines, R. B. et al. Lancet 388, 898–904 (2016).

    Article  CAS  Google Scholar 

  33. Miner, J. J. et al. Cell 165, 1081–1091 (2016).

    Article  CAS  Google Scholar 

  34. Noronha, L., Zanluca, C., Azevedo, M. L., Luz, K. G. & Santos, C. N. Mem. Inst. Oswaldo Cruz 111, 287–293 (2016).

    Article  Google Scholar 

  35. Mesci, P. et al. Hum. Mol. Genet. 27, 41–52 (2018).

    Article  CAS  Google Scholar 

  36. Chavali, P. L. et al. Science 357, 83–88 (2017).

    Article  CAS  Google Scholar 

  37. Wu, K. Y. et al. Cell Res. 26, 645–654 (2016).

    Article  Google Scholar 

  38. Shao, Q. et al. Development 143, 4127–4136 (2016).

    Article  CAS  Google Scholar 

  39. Callender, D. M. Glob. Public Health http://doi.org/crpz (2018).

Download references

Acknowledgements

This work was supported by the European Union’s Horizon 2020 Research and Innovation Programme under ZIKAlliance Grant Agreement No. 734548 (to L.N. and M.L.). L.N. is senior research associate from F.R.S-F.N.R.S. and his research is also supported by F.R.S.-F.N.R.S. (J.0163.16 and J.0028.18 — CDR), the Fonds Léon Fredericq, the Fondation Médicale Reine Elisabeth, the Fondation Simone et Pierre Clerdent, the Belgian Science Policy (IAP-VII network P7/20), the ARC (ARC11/16-01), and the ERANET Neuron STEM-MCD; M.L. is also funded by Institut Pasteur, Inserm and LabEx IBEID.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Marc Lecuit or Laurent Nguyen.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lecuit, M., Nguyen, L. Lessons learnt from the emergence of Zika virus. Nat Microbiol 3, 966–968 (2018). https://doi.org/10.1038/s41564-018-0233-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41564-018-0233-4

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing