Looking back at how Zika virus emergence was handled during and after the 2015–2016 outbreak will be important for assessing how well multiple relevant stakeholders were integrated to mount a response, and can provide the groundwork to better cope with emerging infections in the future.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Macnamara, F. N. Trans. R. Soc. Trop. Med. Hyg. 48, 139–145 (1954).
Duffy, M. R. et al. N. Engl. J. Med. 360, 2536–2543 (2009).
Musso, D. et al. Euro Surveill. 19, 20761 (2014).
Cauchemez, S. et al. Lancet 387, 2125–2132 (2016).
Zika Cumulative Cases (PAHO, WHO, accessed 1 July 2018); https://go.nature.com/2tNktxY
Driggers, R. W. et al. N. Engl. J. Med. 374, 2142–2151 (2016).
Mlakar, J. et al. N. Engl. J. Med. 374, 951–958 (2016).
Hoen, B. et al. N. Engl. J. Med. 378, 985–994 (2018).
Honein, M. A. et al. JAMA 317, 59–68 (2017).
Cao-Lormeau, V. M. et al. Lancet 387, 1531–1539 (2016).
WHO statement on the first meeting of the International Health Regulations (2005) (IHR 2005) Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations. World Health Organization (1 February 2016); https://go.nature.com/2NiMKo2
Zika: Commission activities in the area of Zika (European Commission, 2016); https://go.nature.com/2tRKyMb
Gladwyn-Ng, I. et al. Nat. Neurosci. 21, 63–71 (2018).
Xu, M. et al. Nat. Med. 22, 1101–1107 (2016).
Weaver, S. C., Charlier, C., Vasilakis, N. & Lecuit, M. Annu. Rev. Med. 69, 395–408 (2018).
Laguesse, S. et al. Dev. Cell 35, 553–567 (2015).
Dang, J. et al. Cell Stem Cell 19, 258–265 (2016).
Li, Y. et al. Cell Stem Cell 3, 385–396 (2016).
Qian, X. et al. Cell 165, 1238–1254 (2016).
Watanabe, M. et al. Cell. Rep. 21, 517–532 (2017).
Aliota, M. T. et al. Antiviral Res. 144, 223–246 (2017).
Corman, V. M. et al. Bull. World Health Organ. 94, 880–892 (2016).
Poland, G. A. et al. Lancet Infect. Dis. 18, 211–219 (2018).
Subudhi, B. B., Chattopadhyay, S., Mishra, P. & Kumar, A. Viruses 10, E235 (2018).
Yuan, L. et al. Science 358, 933–936 (2017).
Coelho, F. C. et al. Int. J. Infect. Dis. 51, 128–132 (2016).
McCarthy, M. BMJ 352, i720 (2016).
Duggal, N. K. et al. Cell. Rep. 18, 1751–1760 (2017).
Tang, W. W. et al. Cell. Rep. 17, 3091–3098 (2016).
Moreira, J., Peixoto, T. M., Siqueira, A. M. & Lamas, C. C. Clin. Microbiol. Infect. 23, 296–305 (2017).
Moreira, J., Bressan, C. S., Brasil, P. & Siqueira, A. M. Clin. Microbiol. Infect. 24, 827–835 (2018).
Martines, R. B. et al. Lancet 388, 898–904 (2016).
Miner, J. J. et al. Cell 165, 1081–1091 (2016).
Noronha, L., Zanluca, C., Azevedo, M. L., Luz, K. G. & Santos, C. N. Mem. Inst. Oswaldo Cruz 111, 287–293 (2016).
Mesci, P. et al. Hum. Mol. Genet. 27, 41–52 (2018).
Chavali, P. L. et al. Science 357, 83–88 (2017).
Wu, K. Y. et al. Cell Res. 26, 645–654 (2016).
Shao, Q. et al. Development 143, 4127–4136 (2016).
Callender, D. M. Glob. Public Health http://doi.org/crpz (2018).
Acknowledgements
This work was supported by the European Union’s Horizon 2020 Research and Innovation Programme under ZIKAlliance Grant Agreement No. 734548 (to L.N. and M.L.). L.N. is senior research associate from F.R.S-F.N.R.S. and his research is also supported by F.R.S.-F.N.R.S. (J.0163.16 and J.0028.18 — CDR), the Fonds Léon Fredericq, the Fondation Médicale Reine Elisabeth, the Fondation Simone et Pierre Clerdent, the Belgian Science Policy (IAP-VII network P7/20), the ARC (ARC11/16-01), and the ERANET Neuron STEM-MCD; M.L. is also funded by Institut Pasteur, Inserm and LabEx IBEID.
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Lecuit, M., Nguyen, L. Lessons learnt from the emergence of Zika virus. Nat Microbiol 3, 966–968 (2018). https://doi.org/10.1038/s41564-018-0233-4
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41564-018-0233-4