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Immovable memories: the journey to permanent residency

Frank Carbone describes how his lab identified a new class of memory T cells that permanently reside in the tissues.

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References

  1. Sallusto, F., Lenig, D., Förster, R., Lipp, M. & Lanzavecchia, A. Nature 401, 708–712 (1999).

    Article  CAS  Google Scholar 

  2. Gebhardt, T. et al. Nat. Immunol. 10, 524–530 (2009).

    Article  CAS  Google Scholar 

  3. Khanna, K. M., Bonneau, R. H., Kinchington, P. R. & Hendricks, R. L. Immunity 18, 593–603 (2003).

    Article  CAS  Google Scholar 

  4. Zammit, D. J., Cauley, L. S., Pham, Q. M. & Lefrançois, L. Immunity 22, 561–570 (2005).

    Article  CAS  Google Scholar 

  5. Wakim, L. M., Waithman, J., van Rooijen, N., Heath, W. R. & Carbone, F. R. Science 319, 198–202 (2008).

    Article  CAS  Google Scholar 

  6. Shiohara, T. & Moriya, N. J. Invest. Dermatol. 109, 271–275 (1997).

    Article  CAS  Google Scholar 

  7. Masopust, D., Vezys, V., Marzo, A. L. & Lefrançois, L. Science 291, 2413–2417 (2001).

    Article  CAS  Google Scholar 

  8. Reinhardt, R. L., Khoruts, A., Merica, R., Zell, T. & Jenkins, M. K. Nature 410, 101–105 (2001).

    Article  CAS  Google Scholar 

  9. Clark, R. A. et al. J. Immunol. 176, 4431–4439 (2006).

    Article  CAS  Google Scholar 

  10. Harris, N. L., Watt, V., Ronchese, F. & Le Gros, G. J. Exp. Med. 195, 317–326 (2002).

    Article  CAS  Google Scholar 

  11. Klonowski, K. D. et al. Immunity 20, 551–562 (2004).

    Article  CAS  Google Scholar 

  12. Anderson, K. G. et al. J. Immunol. 189, 2702–2706 (2012).

    Article  CAS  Google Scholar 

  13. Zhu, J. et al. Nature 497, 494–497 (2013).

    Article  CAS  Google Scholar 

  14. Beura, L. K. et al. Immunity 48, 327–338.e5 (2018).

    Article  CAS  Google Scholar 

  15. Masopust, D. et al. J. Exp. Med. 207, 553–564 (2010).

    Article  CAS  Google Scholar 

  16. Mackay, L. K. & Kallies, A. Trends Immunol. 38, 94–103 (2017).

    Article  CAS  Google Scholar 

  17. Gebhardt, T., Palendira, U., Tscharke, D. C. & Bedoui, S. Immunol. Rev. 283, 54–76 (2018).

    Article  CAS  Google Scholar 

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Correspondence to Francis R. Carbone.

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Carbone, F.R. Immovable memories: the journey to permanent residency. Nat Immunol 21, 698–699 (2020). https://doi.org/10.1038/s41590-020-0651-3

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