Issue 10, 1995
From the journal:

Analyst

Electrogenerated chemiluminescent determination of codeine and related alkaloids and pharmaceuticals with tris(2,2′-bipyridine)ruthenium(II)

Gillian M. Greenway,   Andrew W. Knight  and  Paul J. Knight  

Abstract

This work describes a novel and sensitive method for the determination of codeine, heroin, and dextromethorphan, using flow injection with electrogenerated chemiluminescence (ECL). The method is based on the ECL reaction of tris(2,2′-bipyridine)ruthenium(II)[Ru(bpy)22+] with tertiary amino groups. The factors affecting the determinations were investigated and possible reaction inhibitors, such as phenolic functional groups, were identified. Linear calibrations were obtained for signal (mV)versus concentration (µmol l–1) in the range 0.1–1.0 µmol l–1 with percentage relative standard deviations of less than 5%(n= 5). The 5σ limits of detection were calculated as 15, 45 and 44 nmol l–1 for codeine, heroin, and dextromethorphan, respectively.

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/AN9952002549
Article type
Paper

Analyst, 1995,120, 2549-2552

Permissions

Request permissions

Electrogenerated chemiluminescent determination of codeine and related alkaloids and pharmaceuticals with tris(2,2′-bipyridine)ruthenium(II)

G. M. Greenway, A. W. Knight and P. J. Knight, Analyst, 1995, 120, 2549 DOI: 10.1039/AN9952002549

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements