Issue 12, 2006
From the journal:

Chemical Communications

Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

Louis-Charles Campeaua  and  Keith Fagnou*a  

* Corresponding authors

a Center for Catalysis Research and Innovation, University of Ottawa, Departement of Chemistry, 10 Marie Curie, Ottawa, Ontario, Canada
E-mail: Keith.Fagnou@science.uottawa.ca

Abstract

Significant progress has been made in the direct arylation of simple arenes. A number of catalyst systems have been developed which enable the intramolecular direct arylation of aryl chlorides, bromides and iodides in high yield as well as conditions capable of achieving intermolecular direct arylation with simple arenes. This account describes recent progress by our group and others in the development of these reactions.

Graphical abstract: Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

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Article information

DOI
https://doi.org/10.1039/B515481M
Article type
Feature Article
Submitted
01 Nov 2005
Accepted
22 Dec 2005
First published
30 Jan 2006

Chem. Commun., 2006, 1253-1264

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Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules

L. Campeau and K. Fagnou, Chem. Commun., 2006, 1253 DOI: 10.1039/B515481M

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