Issue 19, 2011
From the journal:

Chemical Communications

Palladium-catalyzed C–H bond functionalization of C6-arylpurines†

Hai-Ming Guo,*a   Wei-Hao Rao,a   Hong-Ying Niu,b   Li-Li Jiang,a   Ge Meng,a   Jia-Jia Jin,a   Xi-Ning Yanga  and  Gui-Rong Qu*a  

* Corresponding authors

a College of Chemistry and Environmental Science, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang 453007, Henan, China
E-mail: guohm518@hotmail.com, quguir@sina.com
Fax: 86 373 3329276
Tel: 86 373 3329255

b School of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, China

Abstract

A highly regioselective Pd-catalyzed CAr–H bond activation method was developed for the modification of purines (nucleosides) with different functional groups by using purine as a directing group. This approach provides a new access to a variety of functionalized purines (nucleosides) which are potentially of great importance in medicinal chemistry.

Graphical abstract: Palladium-catalyzed C–H bond functionalization of C6-arylpurines

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC11135C
Article type
Communication
Submitted
25 Feb 2011
Accepted
23 Mar 2011
First published
07 Apr 2011

Chem. Commun., 2011,47, 5608-5610

Permissions

Request permissions

Palladium-catalyzed C–H bond functionalization of C6-arylpurines

H. Guo, W. Rao, H. Niu, L. Jiang, G. Meng, J. Jin, X. Yang and G. Qu, Chem. Commun., 2011, 47, 5608 DOI: 10.1039/C1CC11135C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements