Issue 2, 2012
From the journal:

Nanoscale

SV119-gold nanocage conjugates: a new platform for targeting cancer cellsvia sigma-2 receptors†

Yucai Wang,a   Jinbin Xu,b   Xiaohu Xia,a   Miaoxin Yang,a   Suwanna Vangveravong,b   Jingyi Chen,c   Robert H. Machb  and  Younan Xia*a  

* Corresponding authors

a Department of Biomedical Engineering, Washington University, St Louis, MO, USA
E-mail: xia@biomed.wustl.edu
Fax: (+1) 314-935-7448
Tel: (+1) 314-935-8328

b Department of Radiology, Washington University School of Medicine, St Louis, MO, USA

c Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR, USA

Abstract

We have functionalized the surface of gold nanocages with SV119, a synthetic small molecule specific to sigma-2 receptors, and then demonstrated the capability of this new class of conjugates for targeting cancer cells.

Graphical abstract: SV119-gold nanocage conjugates: a new platform for targeting cancer cellsvia sigma-2 receptors

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Article information

DOI
https://doi.org/10.1039/C1NR11469G
Article type
Communication
Submitted
08 Oct 2011
Accepted
27 Oct 2011
First published
24 Nov 2011

Nanoscale, 2012,4, 421-424

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SV119-gold nanocage conjugates: a new platform for targeting cancer cellsvia sigma-2 receptors

Y. Wang, J. Xu, X. Xia, M. Yang, S. Vangveravong, J. Chen, R. H. Mach and Y. Xia, Nanoscale, 2012, 4, 421 DOI: 10.1039/C1NR11469G

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