Issue 38, 2012
From the journal:

Journal of Materials Chemistry

Specific functionalization of CTAB stabilized anisotropic gold nanoparticles with polypeptides for folding-mediated self-assembly†

Yusong Wang,ab   Daniel Aili,ac   Robert Selegård,c   Yeeyan Tay,b   Lars Baltzer,d   Hua Zhangab  and  Bo Liedberg*ac  

* Corresponding authors

a Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Drive, Singapore 639798
E-mail: bliedberg@ntu.edu.sg

b School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798

c Division of Molecular Physics, Department of Physics, Chemistry and Biology, Linköping University, 581 83 Linköping, Sweden

d Department of Biochemistry and Organic Chemistry, Uppsala University, BMC, Box 576, 751 23 Uppsala, Sweden

Abstract

Anisotropic nanoparticles stabilized by cetyltrimethylammonium bromide (CTAB) are notoriously difficult to homogenously functionalize using conventional gold–thiol chemistry. Using surface assisted laser desorption time of flight mass spectroscopy and scanning transmission electron microscopy-energy dispersive X-ray spectroscopy, we demonstrate that silver species adsorbed on the particle surface prevent effective surface functionalization. When covered by a thin gold film, particle functionalization was drastically improved. A thiol-containing polypeptide was immobilized on arrowhead gold nanorods (NRs) and was subsequently able to selectively heteroassociate with a complementary polypeptide resulting in a folding-mediated bridging aggregation of the NRs. Despite using arrowhead NRs with a pronounced difference in surface arrangement on the {111} facets on the arrowheads compared to the {100} facets at the particle sides, the polypeptides were efficiently and homogeneously immobilized on the particles after gold film overgrowth.

Graphical abstract: Specific functionalization of CTAB stabilized anisotropic gold nanoparticles with polypeptides for folding-mediated self-assembly

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2JM31176C
Article type
Paper
Submitted
25 Feb 2012
Accepted
06 Aug 2012
First published
08 Aug 2012

J. Mater. Chem., 2012,22, 20368-20373

Permissions

Request permissions

Specific functionalization of CTAB stabilized anisotropic gold nanoparticles with polypeptides for folding-mediated self-assembly

Y. Wang, D. Aili, R. Selegård, Y. Tay, L. Baltzer, H. Zhang and B. Liedberg, J. Mater. Chem., 2012, 22, 20368 DOI: 10.1039/C2JM31176C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements