Issue 7, 1977

Rules for ring closure. Stereoelectronic control in the endocyclic alkylation of ketone enolates

Abstract

Endocyclic alkylation of ketone enolates is shown to depend critically upon the size of the so formed ring and six- but not five-membered cyclic ketones can be synthesized in this way; a rationale for this difference is presented.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1977, 233-235

Rules for ring closure. Stereoelectronic control in the endocyclic alkylation of ketone enolates

J. E. Baldwin and L. I. Kruse, J. Chem. Soc., Chem. Commun., 1977, 233 DOI: 10.1039/C39770000233

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