Issue 19, 1988

Synthesis of a chiral nickel(II) complex of an electrophilic glycinate, and its use for asymmetric preparation of α-amino acids

Abstract

A chiral NiII complex of a Schiff's base derived from (S)-o-[(benzylpropyl)amino]benzophenone and α-bromoglycine has been obtained and its stereoselective reaction with nucleophiles studied; the synthesis of aspartic acid with 80% optical purity is described.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1988, 1336-1338

Synthesis of a chiral nickel(II) complex of an electrophilic glycinate, and its use for asymmetric preparation of α-amino acids

Y. N. Belokoń, A. N. Popkov, N. I. Chernoglazova, M. B. Saporovskaya, V. I. Bakhmutov and V. M. Belikov, J. Chem. Soc., Chem. Commun., 1988, 1336 DOI: 10.1039/C39880001336

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