Issue 12, 1989

Synthesis of a kinetically stable yttrium-90 labelled macrocycle–antibody conjugate

Abstract

Lysine is a precursor for the synthesis of an aminobutyl C-functionalised tetra-azacyclododecane tetra-acid which has been linked to B72.3 antibody and may be labelled with 90Y to form a kinetically stable complex of potential use in radioimmunotherapy.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 797-798

Synthesis of a kinetically stable yttrium-90 labelled macrocycle–antibody conjugate

J. P. L. Cox, K. J. Jankowski, R. Kataky, D. Parker, N. R. A. Beeley, B. A. Boyce, M. A. W. Eaton, K. Millar, A. T. Millican, A. Harrison and C. Walker, J. Chem. Soc., Chem. Commun., 1989, 797 DOI: 10.1039/C39890000797

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