SCHEDULED MAINTENANCE
Recent trends in biocatalysis
†a
Thomas
Bayer,
†a
Christoffel P. S.
Badenhorst,
†a
Shuke
Wu,
†a
Mark
Doerr,
†a
Matthias
Höhne
†a
and
Uwe T.
Bornscheuer
*a
Abstract
Biocatalysis has undergone revolutionary progress in the past century. Benefited by the integration of multidisciplinary technologies, natural enzymatic reactions are constantly being explored. Protein engineering gives birth to robust biocatalysts that are widely used in industrial production. These research achievements have gradually constructed a network containing natural enzymatic synthesis pathways and artificially designed enzymatic cascades. Nowadays, the development of artificial intelligence, automation, and ultra-high-throughput technology provides infinite possibilities for the discovery of novel enzymes, enzymatic mechanisms and enzymatic cascades, and gradually complements the lack of remaining key steps in the pathway design of enzymatic total synthesis. Therefore, the research of biocatalysis is gradually moving towards the era of novel technology integration, intelligent manufacturing and enzymatic total synthesis.
- This article is part of the themed collection: Biocatalysis: A cross-journal collection
Please wait while we load your content...
