Issue 12, 2021
From the journal:

Natural Product Reports

Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis

Kang Zhou,a   Song Yangb  and  Shu-Ming Li ORCID logo *c  

* Corresponding authors

a Guizhou University, School of Pharmaceutical Sciences, Huaxi Avenue 2708, Guiyang, China

b Guizhou University, Key Laboratory of Green Pesticide & Agricultural Bioengineering, Ministry of Education, Centre for R&D of Fine Chemicals, Huaxi Avenue 2708, Guiyang, China

c Philipps-Universität Marburg, Fachbereich Pharmazie, Institut für Pharmazeutische Biologie und Biotechnologie, Robert-Koch-Straße 4, Marburg, Germany
E-mail: shuming.li@staff.uni-marburg.de

Abstract

Covering: up to July 2020

Naturally occurring chalcones carrying up to three modified or unmodified C5-, C10-, and C15-prenyl moieties on both rings A and B as well as at the α- and β-carbons are widely distributed in plants of the families of Fabaceae, Moraceae, Zingiberaceae and Cannabaceae. Xanthohumol and isobavachalcone being the most investigated representatives, exhibit diverse and remarkable biological and pharmacological activities. The present review deals with their structural characters, biological activities and occurrence in the plant kingdom. Biosynthesis of prenylated chalcones and metabolism of xanthohumol are also discussed.

Graphical abstract: Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis

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Article information

DOI
https://doi.org/10.1039/D0NP00083C
Article type
Review Article
Submitted
04 Nov 2020
First published
11 May 2021

Nat. Prod. Rep., 2021,38, 2236-2260

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Naturally occurring prenylated chalcones from plants: structural diversity, distribution, activities and biosynthesis

K. Zhou, S. Yang and S. Li, Nat. Prod. Rep., 2021, 38, 2236 DOI: 10.1039/D0NP00083C

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