Issue 11, 1976

Thermodynamic considerations in co-ordination. Part XXII. Sequestering ligands for improving the treatment of plumbism and cadmiumism

Abstract

Potentiometrically determined formation constants are reported for cadmium(II), lead(II), and zinc(II) with ethylenediaminetetra-acetic acid, 1,2,di(2-aminoethoxy)ethanetetra-acetic acid, glutathione, cysteine, and D-penicillamine at 25 °C, I= 3.00M(NaClO4). Computer-simulated models of blood plasma conditions were used to examine the complexing competition between cadmium(II) and zinc(II), and lead(II) and zinc(II), with these ligands. It was concluded that glutathione is the most promising ligand for future clinical studies.

Article information

Article type
Paper

J. Chem. Soc., Dalton Trans., 1976, 1012-1015

Thermodynamic considerations in co-ordination. Part XXII. Sequestering ligands for improving the treatment of plumbism and cadmiumism

A. M. Carrie, M. D. Walker and D. R. Williams, J. Chem. Soc., Dalton Trans., 1976, 1012 DOI: 10.1039/DT9760001012

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements