Issue 10, 2002

Facile and selective deprotection of aryl acetates using sodium perborate under mild and neutral conditions

Abstract

A variety of aryl acetates are cleaved to the corresponding phenols using sodium perborate in methanol under mild conditions (25 °C). The effectiveness of this protocol is manifested in its tolerance of different functional groups and selectivity of deprotection towards aryl acetates whereas alkyl acetates are found to be unreactive under these reaction conditions.

Graphical abstract: Facile and selective deprotection of aryl acetates using sodium perborate under mild and neutral conditions

Article information

Article type
Letter
Submitted
17 Apr 2002
Accepted
01 Aug 2002
First published
16 Sep 2002

New J. Chem., 2002,26, 1273-1276

Facile and selective deprotection of aryl acetates using sodium perborate under mild and neutral conditions

B. P. Bandgar, L. S. Uppalla, V. S. Sadavarte and S. V. Patil, New J. Chem., 2002, 26, 1273 DOI: 10.1039/B203766C

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