Issue 34, 2005

Structure elucidation of a novel family of mycolactonetoxins from the frog pathogen Mycobacterium sp. MU128FXT by mass spectrometry

Abstract

Structures are proposed, based on LC-ion trap MSn analysis and high-resolution FTICR MS/MS analysis, for a novel family of mycolactone toxins isolated from the frog pathogen MU128FXT and differing from those produced by the human pathogen M. ulcerans MUAgy99 in having an altered polyketide side chain.

Graphical abstract: Structure elucidation of a novel family of mycolactone toxins from the frog pathogen Mycobacterium sp. MU128FXT by mass spectrometry

Supplementary files

Article information

Article type
Communication
Submitted
17 May 2005
Accepted
29 Jun 2005
First published
05 Aug 2005

Chem. Commun., 2005, 4306-4308

Structure elucidation of a novel family of mycolactone toxins from the frog pathogen Mycobacterium sp. MU128FXT by mass spectrometry

H. Hong, T. Stinear, P. Skelton, J. B. Spencer and P. F. Leadlay, Chem. Commun., 2005, 4306 DOI: 10.1039/B506835E

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