Issue 3, 2007
From the journal:

Journal of Materials Chemistry

Functional scaffolds of bicontinuous, thermoresponsive L3-phase silica/hydroxyapatite nanocomposites

Jeong Ho Chang,*a   Moo Eon Park,a   Yongsoon Shin,b   Gregory J. Exarhos,b   Kyung Ja Kim,a   Sang Cheon Leea  and  Kyung Sik Oh*c  

* Corresponding authors

a Korea Institute of Ceramic Engineering and Technology, Seoul, Korea
E-mail: jhchang@kicet.re.kr
Fax: +82 2 3282 7811
Tel: +82 23282 2459

b Pacific Northwest National Laboratory, Richland, WA, USA

c Department of Ceramics Engineering, Andong National University, Kyungbuk, Korea
E-mail: ksoh@andong.ac.kr

Abstract

Silicified L3-poly(N-isopropylacrylamide)/hydroxyapatite nanocomposites have been prepared by the integration of a thermosensitive polymer and heterogeneous continuity in a 3-D interconnected porous structure for highly controlled drug release without initial burst release during step-wise temperature changes, and the in-vitro cytotoxicity test for biocompatibility is demonstrated.

Graphical abstract: Functional scaffolds of bicontinuous, thermoresponsive L3-phase silica/hydroxyapatite nanocomposites

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Article information

DOI
https://doi.org/10.1039/B609409K
Article type
Paper
Submitted
03 Jul 2006
Accepted
18 Oct 2006
First published
01 Nov 2006

J. Mater. Chem., 2007,17, 238-242

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Functional scaffolds of bicontinuous, thermoresponsive L3-phase silica/hydroxyapatite nanocomposites

J. H. Chang, M. E. Park, Y. Shin, G. J. Exarhos, K. J. Kim, S. C. Lee and K. S. Oh, J. Mater. Chem., 2007, 17, 238 DOI: 10.1039/B609409K

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