Issue 8, 2009
From the journal:

Green Chemistry

Practical, environment-benign and atom economic KOAc-catalysed deprotection of aryl TIPS ethers under mild fluoride-free conditions†

Bing Wang,*a   Hui-Xia Sun,ab   Bo Chena  and  Zhi-Hua Sun*c  

* Corresponding authors

a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, China
E-mail: wangbing@fudan.edu.cn
Fax: 86-21-54237570
Tel: 86-21-54237570

b Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai, China

c Shanghai Saijia Chemicals Co., Ltd., Suite 402, No. 54, Lane 33, Shilong Road, Shanghai, China
E-mail: sungaris@gmail.com

Abstract

A KOAc-catalysed, fluoride-free protocol not only effects chemoselective deprotection of phenolic TIPS ethers without affecting acetal, ketal, carbamate, O-acetyl and aliphatic silyl ethers, but also improves its atom economy by recycling the silanol byproduct.

Graphical abstract: Practical, environment-benign and atom economic KOAc-catalysed deprotection of aryl TIPS ethers under mild fluoride-free conditions

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B905443J
Article type
Communication
Submitted
18 Mar 2009
Accepted
22 Apr 2009
First published
05 May 2009

Green Chem., 2009,11, 1112-1114

Permissions

Request permissions

Practical, environment-benign and atom economic KOAc-catalysed deprotection of aryl TIPS ethers under mild fluoride-free conditions

B. Wang, H. Sun, B. Chen and Z. Sun, Green Chem., 2009, 11, 1112 DOI: 10.1039/B905443J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements