Issue 11, 2012
From the journal:

Lab on a Chip

Glass/PDMS hybrid microfluidic device integrating vertically aligned SWCNTs to ultrasensitive electrochemical determinations†

Fernando Cruz Moraes,a   Renato Sousa Lima,ab   Thiago Pinotti Segato,ab   Ivana Cesarino,a   Jhanisus Leonel Melendez Cetino,c   Sergio Antonio Spinola Machado,a   Frank Gomezc  and  Emanuel Carrilho*ab  

* Corresponding authors

a Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, Brazil
E-mail: emanuel@iqsc.usp.br
Fax: +55 16 3373 9975
Tel: +55 16 3373 9441

b Instituto Nacional de Ciência e Tecnologia de Bioanalítica, Campinas, Brazil

c California State University Los Angeles, Los Angeles, CA, USA

Abstract

This communication reports a promising platform for rapid, simple, direct, and ultrasensitive determination of serotonin. The method is related to integration of vertically aligned single-walled carbon nanotubes (SWCNTs) in electrochemical microfluidic devices. The required microfabrication protocol is simple and fast. In addition, the nanomaterial influenced remarkably the obtained limit-of-detection (LOD) values. Our system achieved a LOD of 0.2 nmol L−1 for serotonin, to the best of our knowledge one of the lowest values reported in the literature.

Graphical abstract: Glass/PDMS hybrid microfluidic device integrating vertically aligned SWCNTs to ultrasensitive electrochemical determinations

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Article information

DOI
https://doi.org/10.1039/C2LC40141J
Article type
Communication
Submitted
09 Feb 2012
Accepted
20 Apr 2012
First published
24 Apr 2012

Lab Chip, 2012,12, 1959-1962

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Glass/PDMS hybrid microfluidic device integrating vertically aligned SWCNTs to ultrasensitive electrochemical determinations

F. C. Moraes, R. S. Lima, T. P. Segato, I. Cesarino, J. L. M. Cetino, S. A. S. Machado, F. Gomez and E. Carrilho, Lab Chip, 2012, 12, 1959 DOI: 10.1039/C2LC40141J

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