A highly selective ester hydrolase from Pseudomonas sp. for the enzymatic preparation of enantiomerically pure secondary alcohols; chiral auxiliaries in organic synthesis
Abstract
A series of valuable chiral auxiliaries, (R)- and (S)-(1)–(11), have been prepared in high chemical and optical yields by enzymatic hydrolysis of their esters in the presence of a lipase from Pseudomonas sp.