Issue 26, 2017

AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Abstract

A series of new conjugated polyelectrolytes (CPEs) containing tetraphenylethene units are synthesized and characterized. They show apparent aggregation-induced emission (AIE) characteristics and give fluorescence covering from cyan to red with high emission efficiencies in aggregates. These AIE CPEs can directly enter and stain living cells for fluorescence imaging with low cytotoxicity, and can provide information on cellular viscosity at different locations based on fluorescence lifetime imaging.

Graphical abstract: AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Supplementary files

Article information

Article type
Communication
Submitted
04 Apr 2017
Accepted
01 Jun 2017
First published
05 Jun 2017

Polym. Chem., 2017,8, 3862-3866

AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

M. Gao, Y. Hong, B. Chen, Y. Wang, W. Zhou, W. W. H. Wong, J. Zhou, T. A. Smith and Z. Zhao, Polym. Chem., 2017, 8, 3862 DOI: 10.1039/C7PY00564D

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