Issue 3, 2020

Sound-driven dissipative self-assembly of aromatic biomolecules into functional nanoparticles

Abstract

Dissipative self-assembly processes were recently exploited to assemble synthetic materials into supramolecular structures. In most cases, chemical fuel or light driven self-assembly of synthetic molecules was reported. Herein, experimental and computational approaches were used to unveil the role of acoustic cavitation in the formation of supramolecular nanoaggregates by dissipative self-assembly. Acoustic cavitation bubbles were employed as an energy source and a transient interface to fuel and refuel the dissipative self-assembly of simple aromatic biomolecules into uniform nanoparticles. Molecular dynamics simulations were applied to predict the formation of metastable aggregates and the dynamic exchange of the interacting molecules in the nanoaggregates. The intracellular trafficking and dissipative dissolution of the nanoparticles were tracked by microscopy imaging.

Graphical abstract: Sound-driven dissipative self-assembly of aromatic biomolecules into functional nanoparticles

Supplementary files

Article information

Article type
Communication
Submitted
18 Sep 2019
Accepted
11 Dec 2019
First published
11 Dec 2019

Nanoscale Horiz., 2020,5, 553-563

Sound-driven dissipative self-assembly of aromatic biomolecules into functional nanoparticles

S. K. Bhangu, G. Bocchinfuso, M. Ashokkumar and F. Cavalieri, Nanoscale Horiz., 2020, 5, 553 DOI: 10.1039/C9NH00611G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements