Issue 8, 2021

Copper(ii) complex of N-truncated amyloid-β peptide bearing a His-2 motif as a potential receptor for phosphate anions

Abstract

Electrochemical and spectroscopic studies demonstrated that the N-truncated amyloid β peptide Aβ5–9 (Arg-His-Asp-Ser-Gly-NH2) possessing histidine at position 2 (His-2) formed ternary complexes with copper(II) and phosphate anions or phosphate groups of biomolecules. The recognition ability of Cu(II)-Aβ5–9 toward phosphate species provided a new perspective on designing phosphate-selective molecular receptors.

Graphical abstract: Copper(ii) complex of N-truncated amyloid-β peptide bearing a His-2 motif as a potential receptor for phosphate anions

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
12 Nov 2020
Accepted
25 Jan 2021
First published
12 Feb 2021

Dalton Trans., 2021,50, 2726-2730

Copper(II) complex of N-truncated amyloid-β peptide bearing a His-2 motif as a potential receptor for phosphate anions

A. Tobolska, N. E. Wezynfeld, U. E. Wawrzyniak, W. Bal and W. Wróblewski, Dalton Trans., 2021, 50, 2726 DOI: 10.1039/D0DT03898A

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