Low dimensional materials for glucose sensing

Linling Xu; Xianfei Zhang; Zhe Wang; Azhar Ali Haidry; Zhengjun Yao; Enamul Haque; Yichao Wang; Gang Li; Torben Daeneke; Chris F. McConville; Kourosh Kalantar-Zadeh; Ali Zavabeti

doi:10.1039/D1NR02529E

Low dimensional materials for glucose sensing

Linling Xu,^a Xianfei Zhang,^a Zhe Wang,^a Azhar Ali Haidry,

^a Zhengjun Yao,

^a Enamul Haque,

^b Yichao Wang,^c Gang Li,^d Torben Daeneke,

^b Chris F. McConville,

^c Kourosh Kalantar-Zadeh

*^e and Ali Zavabeti

*^d

Author affiliations

* Corresponding authors

^a College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211100, China

^b School of Engineering, RMIT University, Melbourne, VIC, Australia

^c Institute for Frontier Materials, Deakin University, Waurn Ponds, Geelong, VIC, Australia

^d Department of Chemical Engineering, The University of Melbourne, Parkville, VIC, 3010 Australia
E-mail: ali.zavabeti@unimelb.edu.au

^e School of Chemical Engineering, University of New South Wales (UNSW), Kensington, NSW, Australia
E-mail: k.kalantar-zadeh@unsw.edu.au

Abstract

Biosensors are essential components for effective healthcare management. Since biological processes occur on molecular scales, nanomaterials and nanosensors intrinsically provide the most appropriate landscapes for developing biosensors. Low-dimensional materials have the advantage of offering high surface areas, increased reactivity and unique physicochemical properties for efficient and selective biosensing. So far, nanomaterials and nanodevices have offered significant prospects for glucose sensing. Targeted glucose biosensing using such low-dimensional materials enables much more effective monitoring of blood glucose levels, thus providing significantly better predictive diabetes diagnostics and management. In this review, recent advances in using low dimensional materials for sensing glucose are summarized. Sensing fundamentals are discussed, as well as invasive, minimally-invasive and non-invasive sensing methods. The effects of morphological characteristics and size-dependent properties of low dimensional materials are explored for glucose sensing, and the key performance parameters such as selectivity, stability and sensitivity are also discussed. Finally, the challenges and future opportunities that low dimensional materials can offer for glucose sensing are outlined.

This article is part of the themed collection: Recent Review Articles

Nanoscale

Low dimensional materials for glucose sensing

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