Issue 44, 2022

Aqueous Suzuki couplings mediated by a hydrophobic catalyst

Abstract

The catalytic activity of [(Ph2P-o-C6H4)2N]PdCl in aerobic aqueous Suzuki couplings is described. Though hydrophobic, this molecular catalyst is competent in cross-coupling reactions of arylboronic acids with a variety of electronically activated, unactivated, and deactivated aryl iodides, bromides, and chlorides upon heating in aqueous solutions under aerobic conditions to give biphenyl derivatives without the necessity of amphiphiles even in the presence of an excess amount of mercury.

Graphical abstract: Aqueous Suzuki couplings mediated by a hydrophobic catalyst

Supplementary files

Article information

Article type
Paper
Submitted
20 Aug 2022
Accepted
04 Oct 2022
First published
11 Oct 2022
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2022,12, 28862-28866

Aqueous Suzuki couplings mediated by a hydrophobic catalyst

S. Hong and L. Liang, RSC Adv., 2022, 12, 28862 DOI: 10.1039/D2RA05230J

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