SHORT PAPER
Sertoli Cell Tumour in an Amur Tiger

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Abstract

The histological and immunohistochemical characteristics of a malignant Sertoli cell tumour in a 17-year-old Amur tiger (Panthera tigris altaica) are described. Histological examination of the primary lesion in the right testis and metastatic lesions throughout the internal organs showed a variable cellular pattern with an admixture of tubular structures divided by fine stroma filled with fusiform to stellate cells, and sheets of polygonal cells with abundant vacuolated cytoplasm. Immunohistochemical techniques demonstrated strong positive staining for neuron-specific enolase and variable positive staining for vimentin in neoplastic cells, supporting a diagnosis of a tumour of Sertoli cell origin.

References (10)

  • M.P. DeMiguel et al.

    Intermediate filaments in the Sertoli cells of the ageing human testis

    Virchows Archiv

    (1997)
  • Z. Hruban et al.

    Complex mammary carcinoma in a tiger (Panthera tigris)

    Journal of Zoo Animal Medicine

    (1988)
  • M. Miettinen et al.

    Intermediate filament proteins in human testis and testicular germ-cell tumors

    American Journal of Pathology

    (1985)
  • G.A. Niehans et al.

    Immunohistochemistry of germ cell and trophoblastic neoplasms

    Cancer

    (1988)
  • K. Nielsen et al.

    Malignant Sertoli cell tumour of the testis. An immunohistochemical study and review of the literature

    Acta Pathologica Microbiologica et Immunologica Scandinavica

    (1988)
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