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DOI: 10.1055/s-0029-1234966
Antibacterial activity of extract Curcuma amada against Staphylococcus aureus
Staphylococcus aureus is an important pathogen and produce widespread infections. Increasing of antibiotic usage for S. aureus infections, created antibiotic resistance and subsequently to produce new antibiotics. Medicinal herbs with antimicrobial activity have been important role in traditional medicine. The purpose of this study was to determine the antibacterial activity of hydroalcoholic extract from root of Curcuma amada against S. aureus (25923 ATTC).
The roots of C. amada were collected from India and its hydroalcoholic extract (1mg: 5ml) by maceration method was prepared and then its antibacterial activity against S. aureus was evaluated by disk diffusion and broth serial dilution methods (0.039, 0.078, 0.156, 0.312, 0.625, 1.25, 2.5, 5, 10, 20, 40) for determination of MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentration).
The results from the antibacterial tests demonstrated that C. amada hydroalcoholic extract had been effected against S. aureus. The MIC and MBC of the extract against the S. aureus were 2.5 and 5mg/ml, respectively.
This study demonstrated that hydroalcoholic extract of C. amada have excellent antibacterial activities against S. aureus and are beneficial to human health. They have the potential to be used for medical purposes and to be utilized as antibacterial additives in making paper products. However, we need more investigation in vitro and in vivo.